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A gene on chromosome 19p13 that encodes an essential peptidylprolyl isomerase, which regulates mitosis by interacting with NIMA and downregulating its mitosis-promoting activity. PIN1 downregulates BTK’s kinase activity, transactivates multiple oncogenes and induces centrosome amplification, chromosome instability and cell transformation. PIN1 is required for efficient dephosphorylation and recycling of RAF1 after mitogen activation.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


1. Date of death.
2. Date of discharge.
3. Dead/died of disease.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
The U.S. Department of Defense has long alleged that the epidemic was caused by an accident at a nearby biological warfare facility.
Amazon CEO said at the Wired 25th anniversary summit in San Francisco that tech companies should support the U.S. Department of Defense in the wake of Bezos' Blue Origin being awarded a $500M deal with the Pentagon for the development of the New Glenn rocket, CNBC reports.
Summary: Members of the Lebanese Army began Tuesday to distribute 20,000 coats donated by the U.S. Department of Defense to elementary and secondary students in public schools across Lebanon.
Armed Forces on Tuesday.The agreement was signed between the Ministry of Transport and Communications of the Kyrgyz Republic and the U.S. Department of Defense at the end of the meeting.
WASHINGTON, D.C., Oct 15, 2009 (TUR) -- U.S. Department of Defense said that the United States worked with participating governments last week to postpone the international part of "Anatolian Falcon" exercise, and there was a decision made by the government of Turkey to change the concept of the scenario in a way that would not enable the U.S.
The U.S. Department of Defense, through AMC, has identified effective casting design as an invaluable tool to reduce costs and improve the readiness of the U.S.
General Services Administration and the U.S. Department of Defense.
Third, make analogies memorable.The U.S. Department of Defense often summarized its enormously complex budget by saying that it created sufficient military strength for our country to engage in one major war and one minor war at the same time.
military agencies for resale abroad through post exchanges are qualified export receipts; however, sales to the U.S. Department of Defense (DOD) for resale abroad at military commissaries are not.
Air Force and Army, the U.S. Department of Defense, including the armed forces units, and the U.S.
Unisys Corporation (NYSE:UIS) has been awarded a five-year blanket task order for the U.S. Department of Defense's Counterintelligence Field Activity (CIFA), the department's primary counterintelligence coordinating body.
The FileNet Records Manager suite is designed to address specific needs around issues of complying with reporting provisions of the Sarbanes-Oxley Act and to meet the U.S. Department of Defense's 5015.2 records management standards requirement, as well as the U.K.'s National Archives 2002 revised functional requirements.

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