Tzanck test

(redirected from Tzanck smear)

Tzanck test

(tsahnk),
the examination of fluid from a bullous lesion for Tzanck cells (altered epithelial cells, rounded and devoid of intercellular attachments). The periphery of these cells is basophilic and the nucleus is spheric and enlarged with prominent nucleoli; they are characteristic of lesions due to varicella, herpes zoster, herpes simplex, and pemphigus vulgaris.

Tzanck test

(tsănk)
[Arnault Tzanck, Russ. dermatologist in Paris, 1886–1954]
The examination of cells scraped from the lower surface of a vesicle to determine the underlying disease (e.g., infection with a herpesvirus).

Tzanck,

Arnault, Russian dermatologist, 1886-1954.
Tzanck cells - acantholytic epithelial cells seen in the Tzanck test.
Tzanck test - the examination of fluid from a bullous lesion for Tzanck cells.
References in periodicals archive ?
Tzanck smear combined with DIF is used as an effective and simple tool, in the rapid diagnosis of PV.
KOH preparations, Tzanck smear and histopathology was carried out.
Procedures performed on pediatric consult patients Procedure Number Biopsy 98 Culture 37 Tzanck smear 15 Potassium Hydroxide Preparation (KOH) 12 Intralesional steroid injection 1 Incision and drainage 1 TOTAL PROCEDURES 164 Table 4.
HSV is best detected with cytologic detection (Tzanck smear).
Kehkeshan Tahir made a presentation on role of direct immunofluorescence on Tzanck smear and plucked hair in the diagnosis of pemphigus.
Keywords: Eczema herpeticum, Burns, Herpes simplex, Tzanck smear, Acyclovir.
Investigational reports like Grams stain and culture, FNAC, tissue smear, urethral smear, Tzanck smear, KOH, wet mount preparations, chest X-ray along with serological tests like ELISA, Rapid tests for HIV, RPR, VDRL and TPHA for syphilis were noted.
Tzanck smear was done in 5 patients with skin lesion and all were positive.
What is the disadvantage of Tzanck smear test for detection of HSV?
Our diagnosis was made based on clinical features, Tzanck smear, serology and histological examination.
Reintroducing the Tzanck smear. Am J Clin Dermatol.