ERBB4(redirected from Tyrosine kinase-type cell surface receptor HER4)
ERBB4A gene on chromosome 2q33.3-q34 that encodes a single-pass type-1 membrane protein member of the Tyr protein kinase family and the epidermal growth factor receptor subfamily. ERBB4 binds to and is activated by neuregulins and other factors, and it induces various cellular responses, including mitogenesis and differentiation.
ERBB4 mutations have been associated with cancer.
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