TYK2

(redirected from Tyrosine kinase 2)
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TYK2

A gene on chromosome 19p13.2 that encodes a non-receptor protein tyrosine kinase, which phosphorylates IFN-alpha/beta receptor alpha chains and may be involved in intracellular signal transduction by initiating type-I IFN signalling.

Molecular pathology
TYK2 defects cause protein-tyrosine kinase 2 deficiency.
References in periodicals archive ?
Exposure to R5 gp120 and X4 gp 120 resulted in activation of pro line-rich tyrosine kinase 2 (Pyk2), a non-receptor tyrosine kinase related to focal adhesion kinase.

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