type II collagen

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type II col·la·gen

collagen unique to cartilage, nucleus pulposis, notochord, and vitreous body; it forms as thin highly glycosylated fibrils.
References in periodicals archive ?
In the congenita variant, there is abnormal synthesis of type-II collagen and abnormalities are present at birth and may include short trunk, dwarfism with short limbs (proximal and middle), disproportionately larger hands and feet and flat face; while in the tarda variant, there is normal appearance at birth and short trunk becomes apparent around five to six years of age1,2.
Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis.
Research has shown that a combination of undenatured type-II collagen (UC-II[R]) and tetrahydroiso-alpha acids (ThiAA) help revitalize joint function and performance.
Wheatley et al., "Sox9 directly regulates the type-II collagen gene," Nature Genetics, vol.
The researchers also noted that PQQ may be able to attenuate certain enzymes (such as matrix metalloproteinases) that degrade a protein called type-II collagen present in our joints.
Efficacy and safety of glycosylated undenatured type-II collagen (UC-II) in therapy of arthritic dogs.
The results showed that chitosan modification of the PLCL scaffold improved cell compatibility without significant alteration of the physical elastomeric properties of PLCL and resulted in formation of cartilage tissue with better quality [33].Coincidentally, another study fabricated chitosan-modified poly PLCL scaffolds to simulate the main biochemical components of cartilage, which revealed that the chitosan-modified PLCL scaffolds not only could promote cell adhesion and proliferation, but also could significantly enhance excretion of aggrecan and type-II collagen [34].
Holmdahl, "Identification of an immunodominant type-II collagen peptide recognized by T cells in H-2(q) mice: self tolerance at the level of determinant selection," European Journal of Immunology, vol.
Wang et al., "Oral administration of type-II collagen peptide 250-270 suppresses specific cellular and humoral immune response in collagen-induced arthritis," Clinical Immunology, vol.
Research has shown that a combination of undenatured type-II collagen (UC-II[R]) and tetrahydro-iso-alpha acids (ThiAA) help revitalize joint function and performance.
Efficacy and safety of glycosylated undenatured type-II collagen (UC-II[R]) in therapy of arthritic dogs.

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