DIO2

(redirected from Type 2 DI)

DIO2

A gene on chromosome 14q24.2-q24.3 that encodes a protein of the iodothyronine deiodinase family which activates thyroid hormone, converting prohormone thyroxine (T4) by outer-ring deiodination to bioactive 3,3’,5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas.
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From reports that slashing the amount of sugar in sweetened drinks by 40% could prevent 300,000 cases of Type 2 di T abetes, to news that the average five-year-old consumes the equivalent of their own body weight in sugar in a year, reducing the white stuff has become something a national priority.