DIO1

(redirected from Type 1 DI)

DIO1

A gene on chromosome 1p33-p32 that encodes a thiol-requiring propylthiouracil-sensitive oxidoreductase. DIO1 activates thyroid hormone by converting the prohormone thyroxine (T4) by outer-ring deiodination to bioactive 3,3’,5-triiodothyronine (T3). It also degrades T3 and T4 by inner-ring deiodination.
References in periodicals archive ?
London integrated diabetes and mental health pathway for the treatment of type 1 diabetes with disordered eating and insulin reduction.A regional pilot to trial, test and evidence the impact of an integrated diabetes mental health pathway for the assessment, referral and treatment of type 1 di...Red eating and insulin reduction (t1ed).This pilot is open to any suitable qualified provider however the commissioner recognises that due to the specialist nature of the service it is likely to be acute or mental health provider who are most suitable to leading this pilot initiative in london.