Turcot syndrome


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Tur·cot syn·drome

(tur-kō'), [MIM*276300]
a rare and distinctive form of multiple intestinal polyposis associated with brain tumors; autosomal recessive inheritance, caused by mutation in one of the mismatch repair genes: either MLH1 on chromosome 3p, PMS2 on chromosome 7p, or the adenomatous polyposis coli gene (APC) on 5q.

Tur·cot syn·drome

(tur-kō'), [MIM*276300]
a rare and distinctive form of multiple intestinal polyposis associated with brain tumors; autosomal recessive inheritance, caused by mutation in one of the mismatch repair genes: either MLH1 on chromosome 3p, PMS2 on chromosome 7p, or the adenomatous polyposis coli gene (APC) on 5q.

Turcot syndrome

A widely used synonym for what is preferentially termed mismatch repair cancer syndrome, see there.

Turcot syndrome

Oncology A syndrome characterized by multiple colon polyps and brain tumors–eg, ependymoma, glioblastoma, medulloblastoma

Turcot,

Jacques, Canadian surgeon, 1914–.
Turcot syndrome - a rare and distinctive form of multiple intestinal polyposis associated with brain tumors.
References in periodicals archive ?
Turcot Syndrome was originally described as a rare variant of FAP, in which brain tumors develop concurrently with those of the colon and rectum.
It is an advocacy group for families who have any one of the inherited forms of colon cancer, which include familial adenomatous polyposis or Gardner syndrome (FAP/GS), juvenile polyposis (JP), Peutz-Jeghers syndrome, hereditary non-polyposis colon cancer (HNPCC/Lynch syndrome) and Turcot syndrome.
See also: Brain Injury, Cancer, Epilepsy, Turcot Syndrome, Von Hippel-Lindau Syndrome