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A gene on chromosome 3q21-q23 that encodes a member of the ephrin-B receptor subfamily of receptor tyrosine kinases, which “promiscuously” bind membrane-bound ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signalling into neighbouring cells. EPHB1 regulates retinal axon guidance, ipsilaterally redirecting ventrotemporal retinal ganglion cells axons at the optic chiasm midline during nervous system development, a process that is thought to require repulsive interaction with EFNB2. In the adult nervous system, EPHB1 and EFNB3 regulate chemotaxis, proliferation and polarity of the hippocampus neural progenitors.

In addition to its role in axon guidance, EPHB1 also plays a key redundant role with other ephrin-B receptors in development and maturation of dendritic spines and synapse formation. It may also regulate angiogenesis and play a role in targeted cell migration by activating the MAPK/ERK cascade, and in adhesion by activating the JNK signalling cascade. EPHB1’s cognate/functional ephrin ligands include EFNB1, EFNB2 and EFNB3.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


Ears–nose and throat, lungs, kidneys An acronym for the organs involved in Wegener's granulomatosis–WG; limited WG spares the kidneys and lacks signs of systemic vasculitis; generalized WG involves the kidneys and/or has signs of systemic vasculitis; disease exacerbation is best monitored by measuring titers of antineutrophil cytoplasmic antibodies by indirect immunofluorescence. See Wegener's granulomatosis.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Hence, we accept our hypotheses that development of sightability correction factors would reduce risk and decrease costs associated with demographic studies of tule elk. Tests of the third hypothesis, that sightability correction factors would yield more meaningful data, await the results of future surveys during which censuses will be compared with results corrected for visibility bias.
So, in that spirit, brown bears become wild' boars, grizzly bears equal javelinas, polar bears are coyotes, Quebec-Labrador caribou are bobcats, Tule elk are fox, mountain goat are feral goats, bighorn sheep are feral rams (Merino, Barbary or Mouflon), Dall's sheep are cottontail rabbits, desert bighorns are jackrabbits and Stone's sheep are snowshoe hares.
Coastal blacktail and wild hog meat graces many a California country table, and it's the only place where the lucky hunter can pursue tule elk. Crossbows are legal for all during gun seasons, and by providing a physician's letter to the California F&G--and carrying a copy while hunting--disabled hunters may legally use a crossbow during archery seasons.
I had already taken a Tule elk long before P&Y added that species to the list, and I immediately bagged a pair of central Canada barren ground caribou when that variety was added.
A new tower for viewing tule elk should be completed soon.
Tule elk rut in early August, but the bugling season for most elk is late September, although with our later autumns this shades into early October.
The Tule elk is the smallest of the three North American elk species and can only be hunted in California.
Down Cache Creek for the bald eagles and tule elk The remote headwaters of Cache Creek rank second in California as habitat for two impressive wildlife species.
At that time, the Super Slam comprised 27 categories of big game, but with the addition of central Canada barren ground caribou and Tule elk, it now comprises 29 categories.