tubulin

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Related to Tubulins: alpha tubulin

tubulin

 [too´bu-lin]
the constituent protein of microtubules; thought to be involved in phagocyte motility.

tu·bu·lin

(tū'byū-lin),
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein.

tubulin

/tu·bu·lin/ (too´bu-lin) the constituent protein of microtubules.

tubulin

(to͞o′byə-lĭn, tyo͞o′-)
n.
A globular protein that is the basic structural constituent of microtubules.

tu·bu·lin

(tū'byū-lin)
A protein subunit of microtubules; it is a dimer composed of two globular polypeptides, α-tubulin and β-tubulin.
See also: dynein

tubulin

A contractile protein that forms microtubules. These form the spindle fibres in MITOSIS that draw chromosomes apart is the course of cell division.

tubulin

a globular protein molecule, similar to ACTIN, that is the building block of microtubules within the cytoplasm of cells.

tubulin

the constituent protein of microtubules of cells which provide a skeleton for maintaining cell shape and is thought to be involved in cell motility.

α-tubulin
with β-tubulins contributes to the heterodimer tubulin, the building blocks of the electron microscopically visible cell components, the microtubules.
β-tubulin
one of the monomeric globular proteins which associate to form the dimer, α,β-tubulin, the basis of microfilaments.
References in periodicals archive ?
Identification of [alpha]-tubulin, a new member of the tubulin superfamily encoded by mipA gene of Aspergillus nidulans.
Microtubules define neuronal architecture, regulate synapses, and are suggested to process information via interactive bit-like states of tubulin.
Using molecular modeling, Craddock et al reveal a perfect match among spatial dimensions, geometry and electrostatic binding of the insect-like CaMKII, and hexagonal lattices of tubulin proteins in microtubules.
Previous studies showed that ENMD-1420 inhibits tubulin polymerization and TNF-alpha production, contributing to its antiproliferative activity through apoptosis.
EntreMed Vice President and Chief Medical Officer, stated, "We continue to make good progress on our tubulin inhibitor program.
4 indicate that there has been extensive and continuous duplication of tubulin genes throughout the evolution of organisms.
Post-translational tubulin modifications in spermatogeneous cells of the pteridophyte Ceratopteris richardii.
Microtubules however are not passive elements in the vesicle transport and it has been shown that the tubulin C--terminal tails modulate kinesin function.
Microtubules do not only regulate motor protein function but also attach with their C--terminal tubulin tails different MAPs and protein kinases and phosphatases, thus organizing the intraneuronal space.
Celgene's dual-acting tubulin inhibitors strengthen our preclinical oncology pipeline with compounds that attack tumor cells directly and the blood vessels that nourish them.
ZIO-301 (indibulin) is a novel synthetic anti-mitotic agent that binds to tubulin, destabilizes microtubulin polymerization, and arrests tumor cell growth at the G2/M phase.
EntreMed will provide all resources needed to conduct clinical research and regulatory activities associated with seeking marketing approvals of the tubulin inhibitors for oncology applications.

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