triptorelin

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triptorelin

 [trip″to-rel´in]
a synthetic analogue of gonadorelin that on prolonged administration suppresses gonadotropin release; used as triptorelin pamoate as an antineoplastic in the palliative treatment of prostatic carcinoma, administered intramuscularly.

triptorelin

/trip·to·rel·in/ (trip″to-rel´in) a synthetic gonadorelin analogue that on prolonged administration suppresses gonadotropin release; used as t. pamoate as an antineoplastic in the treatment of prostatic carcinoma.

triptorelin

a gonadotropin-releasing hormone used to treat advanced prostate cancer.

triptorelin

Therapeutics A long-acting gonadotropin-releasing hormone analogue, that induces intense reversible hypogonadism by inhibiting LH and, to a lesser degree, FSH release, resulting in ↓ testosterone Indications Advanced prostate and ovarian CA; it may have a role in Rx-refractory sexual deviancy. See Paraphilia.

triptorelin

A synthetic gonadotrophin-releasing hormone used to treat advances cancer of the PROSTATE GLAND. A brand name is Decapeptyl SR.
References in periodicals archive ?
For instance, it was shown that an analogue of gonadotropin-releasing hormone (GnRH), tryptorelin, exerts a biphasic growth effect on ovarian cancer cells (that express GnRH binding sites), by a mechanism of diminished autocrine production of IGF-2 (37).