Tryptorelin | definition of Tryptorelin by Medical dictionary
triptorelin (redirected from Tryptorelin)
a synthetic analogue of gonadorelin
that on prolonged administration suppresses gonadotropin
release; used as triptorelin pamoate
as an antineoplastic
in the palliative treatment of prostatic carcinoma, administered intramuscularly.
triptorelin /trip·to·rel·in/ (trip″to-rel´in) a synthetic gonadorelin analogue that on prolonged administration suppresses gonadotropin release; used as t. pamoate as an antineoplastic in the treatment of prostatic carcinoma.
a gonadotropin-releasing hormone used to treat advanced prostate cancer.
triptorelin Therapeutics A long-acting gonadotropin-releasing hormone analogue, that induces intense reversible hypogonadism by inhibiting LH and, to a lesser degree, FSH release, resulting in ↓ testosterone Indications Advanced prostate and ovarian CA; it may have a role in Rx-refractory sexual deviancy. See Paraphilia.
triptorelin A synthetic gonadotrophin-releasing hormone used to treat advances cancer of the PROSTATE GLAND. A brand name is Decapeptyl SR.
References in periodicals archive
For instance, it was shown that an analogue of gonadotropin-releasing hormone (GnRH), tryptorelin
, exerts a biphasic growth effect on ovarian cancer cells (that express GnRH binding sites), by a mechanism of diminished autocrine production of IGF-2 (37).