KLK11

(redirected from Trypsin-like protease)

KLK11

A gene on chromosome 19q13.33 that encodes a possible multifunctional serine protease which is expressed in the brain, skin and prostate.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
Mentioned in ?
References in periodicals archive ?
According to our data the wastes of sera production are a promising initial biomaterial for trypsin-like protease inhibitor obtain with antiviral properties and lower allergenicity.
The highest content of trypsin-like protease inhibitor was recorded in the fraction of the 5th isoform, which was the latter eluted from the column 0.5 M NaCl, and the least - in the 4th and 3rd isoforms which eluted from the column with 0.2 M and 0.1 NaCl, correspondingly.
Proteolytic activation of seasonal human IAV HA occurs extracellularly or on the cell membrane in the airway by trypsin-type proteases, such as tryptase Clara, (19) mini-plasmin, (7) trypsin, (3) ectopic pancreatic trypsin, (4),(8),(10),(11),(21) porcine lung tryp tase, (22) TC30 (23) and type-II membrane bound proteases, human airway trypsin-like protease (HAT), transmembrane serine protease (TMPRSS)2 (24) and TMPRSS4 (25) (Table 1).
Matriptase (also known as MT-SP1, ST14, TADG-15 and epithin) is a trypsin-like protease from the family of type II transmembrane serine proteases.
gemmatalis cuticle did not have a positive effect on trypsin-like protease (Pr2), since it was produced in substantive amounts in defined growth substrate (nitrate medium).
This shedding may be caused by trypsin-like protease activity, and the presence of such factors in BT products suggests a carryover of fermentation products as noted for [Beta]-lactamase (5,13).
"The action of inhibitor of trypsin-like protease on influenza infection at the conditions of experiment", Infect Dis., Vol.2, pp.35-39
Trypsin-like proteases recognize highly basic residues in a substrate, and these enzymes are critical to Bt protoxin activation to enable midgut binding.
When the activities of protease (trypsinlike, chymotrypsin-like and elastase like) were compared at different pH, no significant differences were found; however, trypsin-like proteases shown the higher activity.
Entomopathogenic fungi produce distinct extracellular serine proteases, such as subtilisin-like proteases, trypsin-like proteases, metalloproteases, as well as several families of exo- acting peptidases that are believed to be important for host cuticle degradation (St.
The high content in basic residues of AMPs favors degradation by the trypsin-like proteases (Andreu & Rivas 1998), as observed in our experiments.