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a multispecies genus of protozoa parasitic in the blood and lymph of invertebrates and vertebrates, including humans; most species live part of their life cycle in the intestines of insects and other invertebrates, the typical adult stage being found only in the vertebrate host. T. gambien´se and T. rhodesien´se cause the Gambian and Rhodesian forms of African trypanosomiasis in humans, and T. cru´zi causes American trypanosomiasis. Other species cause diseases in domestic animals.
Life cycle of the etiologic agents of sleeping sickness (Trypanosoma gambiense and T. rhodesiense). From Mahon and Manuselis, 2000.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.


(tri-pan'ō-sō'mă, trip'ă-nō-),
A genus of asexual digenetic protozoan flagellates (family Trypanosomatidae) that have a spindle-shaped body with an undulating membrane on one side, a single anterior flagellum, and a kinetoplast; they are parasitic in the blood plasma of many vertebrates (only a few being pathogenic) and as a rule have an intermediate host, a bloodsucking invertebrate, such as a leech, tick, or insect; pathogenic species cause trypanosomiasis in humans and other diseases in domestic animals.
[G. trypanon, an auger, + sōma, body]
Farlex Partner Medical Dictionary © Farlex 2012


A genus of asexual digenetic protozoan flagellates that are parasitic in the blood plasma of many vertebrates and as a rule have an intermediate host, a bloodsucking invertebrate such as a leech, tick, or insect; pathogenic species cause trypanosomiasis in humans.
[G. trypanon, an auger, + sōma, body]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(tri-pan″ŏ-sō-mă) [Gr. trypanon, borer + Gr. sōma, a body]
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TRYPANOSOMA CRUZI: (Orig. mag. ×1000)
A genus of parasitic, flagellate protozoa found in the blood of many vertebrates, including humans. The protozoa are transmitted by insect vectors. The only two species relevant for disease in humans are T. brucei and T. cruzi. See: illustration

Trypanosoma brucei

A species with three subspecies: T. brucei brucei, T. brucei gambiense, and T. brucei rhodesiense. The subspecies T. brucei brucei causes a wasting disease in cattle called nagana but does not produce disease in humans. The subspecies T. brucei gambiense causes African sleeping sickness in western and central Africa. The subspecies T. brucei rhodesiense, transmitted by the tsetse fly, causes African sleeping sickness in eastern and southern Africa.

Trypanosoma cruzi

The causative agent of American trypanosomiasis (Chagas disease). It is transmitted by triatomids (bloodsucking insects of the family Reduviidae).
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References in periodicals archive ?
The diagnostic technique for Trypanosoma was wet and thin smear method as described by Khosravi et al.
A mini-exon multiplex polymerase chain reaction to distinguish the major groups of Trypanosoma cruzi and T rangeli in the Brazilian Amazon.
Enzyme D-isomer specific 2-hydro xyacid dehydrogenase, whose expression levels was altered only in the Bolivia strain (Table 3, spot 3), was one of the proteins identified in the present work This enzyme is responsible to catalyze the NAD-dependent oxidation of R-lactate to pyruvate and is part of the detoxification pathway of methylglyoxal (dependent of glyoxalase I, glyoxalase II and low molecular mass thiols) in trypanosomatids, and data from Trypanosoma conorhini and Crithidia fasciculata showed activation in the presence of cysteine.
Caracterizacion parasitologica de Trypanosoma cruzi de aislados obtenidos de mamiferos cinegeticos de tamano grande.
Table 2: Thermodynamic parameters, binding constant (K), and number of binding sites (n) estimated for the interaction between arginine kinase of Trypanosoma brucei (TbAK) and gallotannin.
van-Wynsberghe, Infeccion natural con Trypanosoma cruzi en roedores silvestres de la peninsula de Yucatan.
cruzi: Trypanosoma cruzi TNF-[alpha]: Tumor necrosis factor-alpha TMB: 3,3,5,5 -Tetramethylbenzidine WT: Wild type.