section]) Per 10% increase in fluoroquinolone prescribing during the previous year; includes ciprofloxacin, gemifloxacin, levofloxacin, moxifloxacin, norfloxacin, ofloxacin, and trovafloxacin
Novel a1-adrenoceptor antagonism by the fluroquinolone antibiotic trovafloxacin
Phenotypic resistance of staphylococcus aureus, selected enterobacteriaceae, and pseudomonas aeruginosa after single and multiple in vitro exposures to ciprofloxacin, levofloxacin, and trovafloxacin
received a black box warning from the FDA in 1998 (Mandell and Tillotson, 2002) costing Pfizer $8.
Prediction of the effects of inoculum size on the antimicrobial action of trovafloxacin
and ciprofloxacin against Staphylococcus aureus and Escherichiacoli in an in vitro dynamic model.
Other fluoroquinolones such as gemifloxacin, sparfloxacin, grepafloxacin, trovafloxacin
, and garenoxacin have been shown to be effective against M.
A recent example is the trial using the antibiotic trovafloxacin
, administered orally, versus Food and Drug Administration-approved parenteral ceftriaxone, during a meningitis outbreak in Nigeria (N.
There was no means of enforcing ethical practices in health research in Nigeria until recent developments following the negative publicity that resulted from testing of the drug trovafloxacin
(Trovan) by the drug company Pfizer during a bacterial (meningococcal) meningitis epidemic in Tudun Wada, Kano, Northern Nigeria, in 1996.
troglitazone, bromfenac, pemoline, tolcapone, trovafloxacin
and benoxaprofen .
Food and Drug Administration's ("FDA") approval for the use of Trovafloxacin
Mesylate ("Trovan") on children in the U.
Prevalence of Helicobacter pylori resistance to metronidazole, clarithromycin, amoxycillin, tetracycline and trovafloxacin
in The Netherlands.
In an effort to gain FDA approval for pediatric use of its new antibiotic, trovafloxacin
mesylate or Trovan, Pfizer sponsored a study in Kano, Nigeria (Abdullahi v.