trophoblast

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Related to Trophoblasts: cytotrophoblast, trophoblast layer

trophoblast

 [trof´o-blast]
the peripheral cells of the blastocyst, which attach the zygote (fertilized ovum) to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.

troph·o·blast

(trof'ō-blast, trō'fō-blast),
The mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself but contribute to formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
Synonym(s): chorionic ectoderm
[tropho- + G. blastos, germ]

trophoblast

/tro·pho·blast/ (tro´fo-blast) the peripheral cells of the blastocyst, which attach the blastocyst to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism.trophoblas´tic

trophoblast

(trō′fə-blăst′)
n.
The outermost layer of cells of the mammalian blastocyst that attaches the fertilized ovum to the uterine wall and serves as a nutritive pathway for the embryo.

tro′pho·blas′tic adj.

trophoblast

[trof′əblast′]
Etymology: Gk, trophe + blastos, germ
the outermost layer of tissue that forms the wall of the blastocyst of placental mammals in the early stages of embryonic development. It functions in the implantation of the blastocyst in the uterine wall and in supplying nutrients to the embryo. At implantation the cells differentiate into two layers: the inner cytotrophoblast, which forms the chorion, and the syncytiotrophoblast, which develops into the outer layer of the placenta. Also called trophectoderm. trophoblastic, adj.

troph·o·blast

(trō'fō-blast)
The mesectodermal cell layer covering the blastocyst, which erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself, but contribute to the formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two-layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
[tropho- + G. blastos, germ]

trophoblast

The outer layer of the BLASTOCYST.

trophoblast

the outermost layer of cells surrounding the BLASTOCYST, consisting of embryonic epithelium, which subsequently encloses all the embryonic structures of the developing mammal and forms the outer layer of the CHORION and the embryonic side of the placenta.

Trophoblast

The tissues that surround an embryo and attach it to the uterus.
Mentioned in: Choriocarcinoma

troph·o·blast

(trō'fō-blast)
Mesectodermal cell layer covering the blastocyst that erodes uterine mucosa and through which embryo receives nourishment from mother.
[tropho- + G. blastos, germ]

trophoblast

the peripheral cells of the blastocyst, which attach the fertilized ovum to the uterine wall and contribute to the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.
References in periodicals archive ?
One might view pregnancy as a time of immune compromise, but we have shown in our laboratories that trophoblasts in fact have inherent resistance to a number of viruses.
We realized that these zones of necrosis are likely occupying the mother's soldiers while the invasive trophoblasts sneak into her arteries, leading to more blood flow to the placenta and a bigger baby," said Kliman.
These authors also demonstrated that uptake of DHEAS by monolayer trophoblast was not influenced by 1.
Eventually this led him to the theory that the trophoblast was itself a kind of "asexual" growth that accompanied the growth of the sexual embryo.
Endometrial cups Clusters of tightly packed cells from the trophoblast that become embedded deeply in the endometrium and produce eCG.
Normal placental development depends on proper trophoblast invasion, vascular remodeling, and maintenance of intervillous blood flow (2).
2003) and Sutherland, (2003), the presence of the estrogen stimulates the morphologic and functional differentiation of the trophoblast during the gestation.
Under most circumstances, decidua can be distinguished from extravillous trophoblast in the implantation site.
Exaggerated placental site was characterized with exaggerated and increased infiltration of endometrium and myometrium by intermediate trophoblasts in the implantation area of the placenta increasing in number.
We previously showed that p-NP acts on human placenta by inducing trophoblast differentiation and apoptosis.
To further investigate the potential role of ficolins in the preeclamptic trophoblasts, we demonstrated the strong expression of apoptotic protein marker Fas protein, and also the coexpression of both ficolins and Fas in the syncytiotrophoblasts from established preeclamptic pregnancies (n = 5; Fig.
All those changes reflect what happens when trophoblasts start to form the placenta.