trophoblast

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Related to Trophoblasts: cytotrophoblast, trophoblast layer

trophoblast

 [trof´o-blast]
the peripheral cells of the blastocyst, which attach the zygote (fertilized ovum) to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.

troph·o·blast

(trof'ō-blast, trō'fō-blast),
The mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself but contribute to formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
Synonym(s): chorionic ectoderm
[tropho- + G. blastos, germ]

trophoblast

/tro·pho·blast/ (tro´fo-blast) the peripheral cells of the blastocyst, which attach the blastocyst to the uterine wall and become the placenta and the membranes that nourish and protect the developing organism.trophoblas´tic

trophoblast

(trō′fə-blăst′)
n.
The outermost layer of cells of the mammalian blastocyst that attaches the fertilized ovum to the uterine wall and serves as a nutritive pathway for the embryo.

tro′pho·blas′tic adj.

trophoblast

[trof′əblast′]
Etymology: Gk, trophe + blastos, germ
the outermost layer of tissue that forms the wall of the blastocyst of placental mammals in the early stages of embryonic development. It functions in the implantation of the blastocyst in the uterine wall and in supplying nutrients to the embryo. At implantation the cells differentiate into two layers: the inner cytotrophoblast, which forms the chorion, and the syncytiotrophoblast, which develops into the outer layer of the placenta. Also called trophectoderm. trophoblastic, adj.

troph·o·blast

(trō'fō-blast)
The mesectodermal cell layer covering the blastocyst, which erodes the uterine mucosa and through which the embryo receives nourishment from the mother; the cells do not enter into the formation of the embryo itself, but contribute to the formation of the placenta. The trophoblast develops processes that later receive a core of vascular mesoderm and are then known as the chorionic villi; the trophoblast soon becomes two-layered, differentiating into the syncytiotrophoblast, an outer layer consisting of a multinucleated protoplasmic mass (syncytium), and the cytotrophoblast, the inner layer next to the mesoderm in which the cells retain their membranes.
[tropho- + G. blastos, germ]

trophoblast

The outer layer of the BLASTOCYST.

trophoblast

the outermost layer of cells surrounding the BLASTOCYST, consisting of embryonic epithelium, which subsequently encloses all the embryonic structures of the developing mammal and forms the outer layer of the CHORION and the embryonic side of the placenta.

Trophoblast

The tissues that surround an embryo and attach it to the uterus.
Mentioned in: Choriocarcinoma

troph·o·blast

(trō'fō-blast)
Mesectodermal cell layer covering the blastocyst that erodes uterine mucosa and through which embryo receives nourishment from mother.
[tropho- + G. blastos, germ]

trophoblast

the peripheral cells of the blastocyst, which attach the fertilized ovum to the uterine wall and contribute to the placenta and the membranes that nourish and protect the developing organism. The inner cellular layer is the cytotrophoblast and the outer layer is the syntrophoblast.
References in periodicals archive ?
Chorionic disc extravillous trophoblasts in placental diagnosis.
Purification and properties of a major, low molecular weight protein relaeased by the trophoblast of sheep blastocysts at day 13-21.
The most common features in these cases were scalloped villous outlines, focal and irregular trophoblast proliferation, and hydrops of the villous stroma.
recently demonstrated that miRNAs are exported from human placental syncytiotrophoblasts into the maternal circulation via exosomes and suggested that circulating trophoblast derived miRNAs reflected the physiological status of the pregnancy and could be used diagnostically (10).
who led the study, explained that in a normal pregnancy, specialized invasive trophoblasts leave the placenta and invade the mother's tissues to attack and destroy the walls of her blood vessels.
In the new study, researchers led by Antonis Makrigiannakis of the University of Crete in Greece examined human trophoblast cells isolated in tissue cultures.
Leptin expression in primary trophoblast cells in response to incubation with the serum of preeclamptic women.
Recurrent miscarriage, preeclampsia, and fetal growth restriction are thought to result from inadequate trophoblast invasion of the uterus lining.
Some embryologists now refer to trophoblast as a "pseudomalignancy.
A cell capture device is used to isolate fetal trophoblasts from the mucus.
In their experiments, described in the January 1999 PLACENTA, they added the gene for the ERV-3 envelope protein to laboratory cultures of trophoblasts, cellular precursors of several placental layers, including the syncytium.
They created an in vitro culture of two key cell types involved in spiral artery development - endothelial cells and trophoblasts and then exposed some to serum from women with normal pregnancies and some to preeclampsia serum from women taken at various stages of their pregnancies.