FSH is a trophic hormone
that is involved in steroidogenesis, energy and metabolism, angiogenesis, protein synthesis, cell division, growth and differentiation --all key mechanisms in carcinogenesis.
If the cause is pituitary-dependent this means the pituitary gland is producing too much adrenocortical trophic hormone
1 illustrates how simultaneous target hormone and trophic hormone measurements can be used to classify endocrine disorders.
An example of paired hormone measurements is serum thyrotropin from the pituitary as the trophic hormone with thyroxine and triiodothyronine from the thyroid gland as target hormones.
Second, StAR protein expression is critically dependent on trophic hormone
stimulation, making it susceptible to xenobiotics that disrupt components of the trophic hormone
The work of the pituitary gland is to suss out when the other glands are under or overworking and bring them back into line through its own super or trophic hormones