Apoptosis process in the target tissue start with the removal of trophic hormone
(Wyllie et al.
FSH is a trophic hormone
that is involved in steroidogenesis, energy and metabolism, angiogenesis, protein synthesis, cell division, growth and differentiation --all key mechanisms in carcinogenesis.
If the cause is pituitary-dependent this means the pituitary gland is producing too much adrenocortical trophic hormone
1 illustrates how simultaneous target hormone and trophic hormone measurements can be used to classify endocrine disorders.
An example of paired hormone measurements is serum thyrotropin from the pituitary as the trophic hormone with thyroxine and triiodothyronine from the thyroid gland as target hormones.
Second, StAR protein expression is critically dependent on trophic hormone
stimulation, making it susceptible to xenobiotics that disrupt components of the trophic hormone
The work of the pituitary gland is to suss out when the other glands are working at the correct level, and bring them back into line through its own super or trophic hormones
Although levels of pituitary trophic hormones
are generally low in this condition, the thyrotrophin (TSH) was normal in seven cases in the present series.
Because of advances in producing various analogues (similar in chemical structure) of the trophic hormones
, long-acting preparations of growth hormone and IGF-I have recentHy become available for investigational use.
The work of the pituitary gland is to suss out when the other glands are under or overworking and bring them back into line through its own super or trophic hormones