Polymerase chain reaction analysis for diagnosis of Tropheryma whippelii infective endocarditis in two patients with no previous evidence of Whipple's disease.
An uncommon cause of recurrent strokes: Tropheryma whippelii endocarditis.
PCR against Tropheryma whippelii
has facilitated diagnosis in recent years.
Another unculturable microbe that has been specifically detected by PCR and probe analysis is Tropheryma whippelii
, the causative agent of Whipple disease [128, 172, 173].
Brief report: uveitis caused by Tropheryma whippelii (Whipple's bacillus).
Tropheryma whippelii DNA in saliva of patients without Whipple's disease.
60,61) Whipple disease, infection by Tropheryma whippelii
, almost always involves the small intestine and mesenteric lymph nodes and causes pericarditis in 75%, endocarditis in 50%, myocardial fibrosis in 10%, and myocarditis in 1% of cases.
The bacteria were thus classified within the family Actinomycetes (classification was based on 16S rDNA sequence analysis), and the name Tropheryma whippelii was proposed (5,6); the bacterium was later modified to Tropheryma whipplei by La Scola et al.
Culture and immunological detection of Tropheryma whippelii from the duodenum of a patient with Whipple disease.
14) The causative agent is a soil-borne gram-positive bacillus Tropheryma whippelii