It is reported that triterpenoid saponins
extracted from Androsace umbellata exhibit cytotoxic activity in several types of cancer cells, including HepG2, Hep3B, A549, HCT15, and Raw 264.
either triterpenoid saponins
or steroid saponins (Wina et al.
have been reported from the plant (Englert et al.
The triterpenoid saponins
occurring in Panax Ginseng are known to have psychoactive properties and therefore there is a possibility that other triterpenoid saponins
found in the Carophyllaceae family may also have psychoactive properties that requires further research.
Recent progress in the synthesis of naturally occurring triterpenoid saponins
The major known bioactive constituents of the plant include polyacetylenes, triterpenoid saponins
(asiaticoside and madecassoside) and sapoogenins.
Anti HIV-1 protease triterpenoid saponins
from the seeds of Aesculus chinensis.
Antioxidant and antiglycation properties of triterpenoid saponins
from Aralia taibaiensis traditionally used for treating diabetes mellitus pp.
These findings are also not restricted to Balanites; triterpenoid saponins
are listed as bioactive consitutents of extracts of several medicinal plants used in Traditional Chinese Medicine, which display plasma glucose lowering activity when tested in STZ-induced diabetic mice (Fie et al.
A previous study reported that CKS contain triterpenoid saponins
, such as deapio-platycoside E, platycoside E, deapioplatycodin D3, platycodin D3, polygalacin D2, platyconic acid A, platycodin D2, platycodin D, and 2'-0-acetylpolygalacin D2 (Noh et al.
with anti-inflammatory activity from Codonopsis lanceolata.
However, it has been recently proved that both, the extract of ivy and triterpenoid saponins
, exhibit strong contractile effect on rat isolated stomach smooth muscle strips.