triptans


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triptans

A group of drugs, known as selective serotonin agonists, with effects similar to those of the neurotransmitter SEROTONIN. Their action is uncertain, but they are thought to act by tightening the branches of the carotid arteries that supply the scalp and brain. They may also act on the main sensory nerve of the face and head. They are effective in controlling the symptoms of MIGRAINE, especially if supplemented by the gastrokinetic drug trimebutine. The group includes almotriptan (Almogran), frovatriptan (Migard), naratriptan (Naramig), rizatriptan (Maxalt), sumatriptan (Imigran), zolmitriptan (Zomig).
References in periodicals archive ?
Triptans were developed to constrict blood vessels and so relieve pain.
Both triptans and nonsteroidal anti-inflammatory drugs (NSAIDs) can be effective treatments for MRM.
Evans suggested the biologic implausibility of triptans causing serotonin syndrome, because serotonin syndrome is believed to be caused by activation of 5-HT1A and 5-HT2A receptors, whereas triptans act at the 5-HT1B/5-HT1D and 5-HT1F receptors.
When treating anxiety/depression concurrently with migraines, which are managed with triptans, there are several treatment options that can be explored.
There are good data for most of the triptans for adolescents aged 12 and older," Dr.
Euromonitor International's OTC Triptans in United Kingdom report offers a comprehensive guide to the size and shape of the market at a national level.
Euromonitor International's OTC Triptans in Kazakhstan report offers a comprehensive guide to the size and shape of the market at a national level.
Euromonitor International's OTC Triptans in Azerbaijan report offers a comprehensive guide to the size and shape of the market at a national level.
The pooled subgroup analysis covered the 187 women with at least one episode of menstrual migraine treated with frovatriptan and one episode treated with one of the other triptans.
At 24 hours of follow-up, the recurrence rate was 11% following frovatriptan versus 24% collectively for the comparator triptans.
This effect seems to be stronger for single analgesics and triptans than for combination analgesics," said Dr.
If not available without a prescription, see your local GP who will be able to offer Triptans in the form of tablets, injections or nasal sprays.