Formulation Adjuvant Adverse reactions Tripedia
Aluminum potassium sulfate 11,178 Daptacel Aluminum phosphate 8,786 Infanrix Aluminum hydroxide 13,238 TABLE 7: Adverse reactions reported in VAERS for sulfate versus hydroxide in age-matched samples, and the likelihood that the contrasts observed in these distributions could have occurred by chance (p < 0.05).
Selected Vaccines That Contain Gelatin Indication Vaccine diptheria, tetanus, and acellular pertussis (DTaP) Tripedia
DTaP/Haemophilus influenzae type B combination TriHIBit influenza Fluzone Jaapanese encephalitis JE-Vax measles, mumps, and rubella (MMR) MMR-II measles, mums, rubella, and varicella (MMRV) ProQuad typhoid (oral form) Vivotif varicella Varivax yellow fever YF-Vax zoster Zostavax Source: The Pink Book 11th ed.
Various other vaccines also contain gelatin, such as Tripedia
(diphtheria, tetanus, and acellular pertussis), Fluzone (influenza), Zostavax (zoster), and Varivax (varicella), said Dr.
In TriHIBit[R], Haemophilus influenzae type b (Hib) vaccine ActHIB[R] is reconstituted with the Tripedia
With the March 2001 approval of a second diphtheria and tetanus toxoid and pertussis vaccine (DTaP) that does not contain thimerosal as a preservative (Aventis Pasteur's Tripedia
, trace thimerosal), all DTaP vaccines currently being produced in the U.S.
production of Tripedia
. Other manufacturers are also developing new vaccines.
Jackson of the University of Washington, Seattle, and her colleagues conducted a randomized, blinded controlled trial within a larger safety study of the Tripedia
or Infanrix for doses 1-4, Acel-Imune for all 5 doses), but whole DTP is an acceptable alternative if no DTaP is available.
, the acellular pertussis (DTaP) vaccine was approved by the FDA for the primary series in infants on July 31, 1996.
Three vaccines are now licensed in the United States: SKB-3P (Infanrix), CB-2 (Tripedia
), and CLL-4[F.sub.2] (DAPTACEL).
The first DTaP vaccine on the US market to get approval for five dose was Tripedia
, manufactured by Aventis Pasteur.
market to get approval for five doses was Tripedia
, made by Aventis Pasteur.