Trinucleotide repeat expansion


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Trinucleotide repeat expansion

A sequence of three nucleotides that is repeated too many times in a section of a gene.
Mentioned in: Myotonic Dystrophy
References in periodicals archive ?
An example is fragile X syndrome, which is the result of a trinucleotide repeat expansion in one region of the genome that can result in autistic behavior, intellectual impairment, and seizures.
A novel PCR-based approach for the detection of the Huntington disease associated trinucleotide repeat expansion.
The abbreviated process likely will be sufficient for all mutations except trinucleotide repeat expansion mutations, which would require special handling as discussed above.