trimethobenzamide


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trimethobenzamide

 [tri-meth″o-ben´zah-mīd]
an antiemetic administered orally, intramuscularly, or rectally as the hydrochloride salt.

trimethobenzamide

/tri·meth·o·ben·za·mide/ (-meth″o-ben´zah-mīd) an antiemetic, used as the hydrochloride salt.

trimethobenzamide (trīmeth´ō-ben´zəmīd´),

n brand name: Arrestin, Bio-Gan, Stemetic, Ticon, Tigan, T-Gen, Triban, others;
drug class: antiemetic;
action: acts centrally by blocking the chemoreceptor trigger zone, which in turn acts on vomiting center;
uses: treatment of nausea and vomiting and prevention of postoperative vomiting.

trimethobenzamide

an ethanolamine derivative; a strong antidopaminergic antagonist which is used as a central antiemetic.
References in periodicals archive ?
This includes, but is not limited to phenothiazines, butyrophenones, hydroxyzine, lorazepam, cannabinoids, metoclopramide, corticosteroids (with the exception of topical steroids for skin disorder and inhaled steroids for respiratory disorders), trimethobenzamide, monoamine oxidase inhibitors, lithium, and 5-HT3 receptor antagonists.
Second, we excluded drugs that were unavailable in Taiwan, including pentazocine, trimethobenzamide, amphetamines, guanadrel, mesoridazine, mineral oil, and desiccated thyroid.
Randomized, placebo-controlled trial of trimethobenzamide to control nausea and vomiting during initiation and continued treatment with subcutaneous apomorphine injection," Parkinsonism and Related Disorders, vol.
Drugs Commonly Used for Treatment of Nausea and Vomiting Dopamine- Antihistamine Drugs Antagonist Drugs Anticholinergic Agents/ Dimenhydrinate Promethazine * Scopolamine (Dramamine[R]) (Phenergan[R]) (Transderm Scop[R]) Meclizine Prochlorperazine Trimethobenzamide (Antivert[R]) (Compazine[R]) (Tigan[R]) Diphenhydramine Metoclopramide (Benadryl[R]) (Reglan[R]) Droperidol (Inapsine[R]) Chlorpromazine (Thorazine[R]) The FDA recently issued a "black box" warning for promethazine regarding the risks of IV push administration.
The antiemetics included ondansetron (six studies), domperidone (two studies), trimethobenzamide (two studies), pyrilaminepentobarbital (two studies), metoclopramide (two studies), dexamethasone (one study), and promethazine (one study).
Tigan and other suppository drug products that contain trimethobenzamide hydrochloride have not been shown to be effective for nausea and vomiting and should no longer be marketed, says the Food and Drug Administration.
Suppositories containing trimethobenzamide, a sedating antihistamine, have been marketed under trade names that include Tigan, Tebamide, T-Gen, Trimazide, and Trimethobenz.
The FDA said patients can use alternative forms of the drug, trimethobenzamide, marketed as capsules or injections by makers including King and Icelandic generic-drug maker Actavis Group hf.
She tried dexamethasone and trimethobenzamide, and that helped to some degree.
Other common oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), and ondansetron (Zofran).
The study also looked at extrapyramidal side effects for those exposed to trimethobenzamide.
Other commonly used oral medications for NVP include prochlorperazine (Compazine), metoclopramide (Reglan), trimethobenzamide (Tigan), promethazine (Phenergan), and ondansetron (Zofran).