Treponema pallidum immobilization test

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Related to Treponema pallidum immobilization test: treponemal


a genus of gram-negative, motile bacteria, spirochetes found in the oral, intestinal, and genital mucosa. Pathogenic species include T. cara´teum, the etiologic agent of pinta; T. pal´lidum subsp. pal´lidum, the etiologic agent of syphilis; and T. pal´lidum subsp. perte´nue, the etiologic agent of yaws.
Treponema pallidum complement fixation test (Treponema pallidum hemagglutinin test) (Treponema pallidum immobilization test) formerly common serological tests for the diagnosis of syphilis, related directly to the causative organism.

Trep·o·ne·ma pal·li·dum im·mo·bi·li·za·tion test

, TPH test
a test for syphilis in which an antibody other than Wassermann antibody is present in the serum of a syphilitic patient, which in the presence of complement causes the immobilization of actively motile T. pallidum obtained from testes of a rabbit infected with syphilis.

Treponema pallidum immobilization test

TPI test A test once the 'gold standard' for the serologic diagnosis of syphilis. Cf Rapid plasma reagin test, VDRL.
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