Treponema pallidum hemagglutination test

Trep·o·ne·ma pal·li·dum he·mag·glu·ti·na·tion test

a highly sensitive and specific test for the serologic diagnosis of syphilis; tanned sheep red blood cells are coated with the antigen of T. pallidum and, after absorption of nonspecific patient serum antibody, a positive reaction with tanned sheep red blood cells and patient serum indicates the presence of specific antibody for T. pallidum in patient serum.

Synonym(s): TPHA test

Treponema pallidum hemagglutination test

TPHA test Lab medicine A nonspecific serologic test for syphilis, in which the Pt's serum is incubated with tanned sheep RBCs previously coated with T pallidum antigens; if syphilis is present, tanned RBCs agglutinate

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References in periodicals archive ?

Miranda, "Comparison of a recombinant-antigen enzyme immunoassay with Treponema pallidum hemagglutination test for serological confirmation of syphilis," Memorias do Instituto Oswaldo Cruz, vol.

Comparison of RPR and ELISA with TPHA for the Diagnosis of Syphilis: Implication for Updating Syphilis Point-of-Care Tests in Ethiopia