(22) See Yael Waknine, FDA Approvals: Risperdal/Risperdal M-TAB, Travatan
Z, Rituxan, MEDSCAPE (Oct.
His 22-tenure at Alcon resulted in his contributions to the discovery and development and US FDA approvals of Travatan
, Patanol, Simbrinza, and Pazeo to treat glaucoma/ocular hypertension and ocular allergies.
Jampel et al., "Adherence with topical glaucoma medication monitored electronically: the Travatan
Dosing Aid study," Ophthalmology, vol.
(24.) Manufacturer's Information: Travatan
(2,4,6) Mechanism Drug Class Preparations of Action Reduction Adrenergic Brimonidine of Aqueous agonists Apraclonidine Inflow [beta]-blockers Non-selective Timolol Levobunolol Carteolol Selective [beta]-blockers Betaxolol Carbonic Systemic anhydrase Acetazolamide inhibitors Methazolamide Dichlorphenamide Topical Dorzolamide Brinzolamide Increase Cholinergics Pilocarpine in Aqueous Increase Carbachol Outflow trabecular outflow Prostaglandins Latanoprost (xalatan) and other lipid Travoprost (travatan
) receptor agonists Increase Bimatoprost (lumigan) uveoscleral Unoprostone outflow Table 2: The Demographic Data of the Patients of POAG Selected for the Study Bimatoprost Timolol Maleate No.
Of the four prostaglandin analogs, three have no human eye data, bimatoprost (Lumigan), tafluprost (Zioptan), and travoprost (Travatan
Latanoprost (Xalatan), travoprost (Travatan
Z) and bimatoprost (Lumigan) are medications in this class used for glaucoma and hypertension of the eye.
Prostaglandin F2[alpha] analoglari (Latanoprost, Xalatan, Pfizer Inc, New York, NY; Travoprost, Travatan
, Alcon, Fort Worth, TX, USA) ve prostaglandin benzeri molekuler yapiya sahip prostamidlerden (prostaglandin etanolamin) tedavi amacli kullanilabilen tek molekul olan Bimatoprost (Lumigan, Allergan, Irvine, CA, USA) gunumuzde okuler hipertansiyon ve glokom tedavisinde onemli yere sahiptir.
Drug Class How it works Dipivefrin Adrenergics Reduces (Propine); intraocular pressure brimonidine (Alphagan) Apraclonidine Alpha-2 Decreases intraocular fluid (Lopidine) adrenergics production; increases drainage Betaxolol Beta blockers Decreases (Betoptic) intraocular fluid production Brinzolamide Carbonic Decreases anhydrase intraocular (Azopt) inhibitors fluid production Pilocarpine Cholinergics Increases drainage of (Isopto) intraocular fluid Dorzolomide Combination Decreases beta blocker/ intraocular (Cosopt) carbonic fluid anhydrase production inhibitor Travaprost Prostaglandin Increases analogs drainage of (Travatan
) intraocular fluid Treatment "Glaucoma is caused by impaired outflow of aqueous humor from the eye," says Dr.
The only medications I am taking are simvastatin and travatan
Based in Fort Worth, TX (where the company was founded), Alcon makes Opti-Free contact lens solution and the popular glaucoma treatment Travatan
Z, but a substantial part of its sales comes from its eye surgery products and devices, too, such as equipment for lens removal and insertion, intraocular lenses to replace the eye's natural lens and sterile surgical kits to streamline surgery.
* Prostaglandin analogs such as travoprost (Travatan
) to increase draining of intraocular fluid.