transplant rejection

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transplant rejection

Graft rejection, organ rejection, tissue rejection Immunology The constellation of host immune responses evoked when an allograft tissue is transplanted into a recipient; rejection phenomena may be minimized by optimal matching of MHC antigens and ABO blood groups and ameliorated with immunosuppressants–eg, cyclosporin, tacrolimus, rapamycin Exceptions of TR Corneal transplants, identical twins. See Graft-versus-host disease, HLA, MHC, Tissue typing.


1. an organ or tissue taken from the body and grafted into another area of the same individual or another individual.
2. to transfer tissue from one part to another or from one individual to another.

ovum transplant
see ovum transplant.
transplant rejection
References in periodicals archive ?
We can say that it does as well if not better than the other immunosuppressive drugs we have now," said Dominic Borie, MD, PhD, senior research scientist and director of transplantation immunology in Stanford's Department of Cardiothoracic Surgery, and senior author of the study that appears in the Oct.
Borie led the Stanford transplantation immunology team that tested the drug's effectiveness in cell cultures and in kidney transplants in monkeys, on the pathway leading to human clinical trials.
Randall Morris, MD, research professor and director of transplantation immunology in the Department of Cardiothoracic Surgery, elevated the drug -- called sirolimus -- from the brink of obscurity to its current role in transplantation.
Blazar is a Professor in the Department of Pediatrics, Division of Hematology, Oncology and Blood and Marrow Transplant at the University of Minnesota in Minneapolis and is the Andersen Chair in Transplantation Immunology.
For this reason, one of the major goals of transplantation immunology is to induce selective immune tolerance, which would alleviate the need for immunosuppression and decrease late allograft failure.
as Senior Director of Molecular and Cellular Biology, conducting research in transplantation immunology and cellular therapy.
Iwaki has held two professorships at the University of Southern California School of Medicine in the Department of Urology and Pathology and has been the Director of the Transplantation Immunology and Immunogenetic Laboratory since 1992.
Iwaki, 46, is the Director, Transplantation Immunology & Immunogenetics Laboratory in the Department of Urology at the University of Southern California and is a Professor of Urology, Surgery, and Pathology at the University of Southern California School of Medicine.
The funds available to Endogen from the transaction with Leeco, expected to be approximately $3 million net of expenses, are intended to be used, among other things, to develop cytokine tests for the clinical and laboratory markets in the growing areas of transplantation immunology and therapeutic drug monitoring.

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