transmissible spongiform encephalopathy

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Related to Transmissible spongiform encephalopathies: Creutzfeldt-Jakob disease

encephalopathy

 [en-sef″ah-lop´ah-the]
any degenerative disease of the brain.
AIDS encephalopathy HIV encephalopathy.
anoxic encephalopathy hypoxic encephalopathy.
biliary encephalopathy (bilirubin encephalopathy) kernicterus.
bovine spongiform encephalopathy a prion disease of adult cattle in the British Isles with neurologic symptoms. It is transmitted by feed containing protein in the form of meat and bone meal derived from infected animals. The etiologic agent is also the cause of new variant Creutzfeldt-Jakob disease. Called also mad cow disease.
boxer's encephalopathy (boxer's traumatic encephalopathy) a syndrome due to cumulative head blows absorbed in the boxing ring, characterized by slowing of mental function, occasional bouts of confusion, and scattered memory loss. It may progress to the more serious boxer's dementia. See also postconcussional syndrome.
dialysis encephalopathy a degenerative disease of the brain associated with longterm use of hemodialysis, marked by speech disorders and constant myoclonic jerks, progressing to global dementia.
hepatic encephalopathy a condition, usually occurring secondary to advanced liver disease, marked by disturbances of consciousness that may progress to deep coma (hepatic coma), psychiatric changes of varying degree, flapping tremor, and fetor hepaticus.
HIV encephalopathy (HIV-related encephalopathy) a progressive primary encephalopathy caused by infection with human immunodeficiency virus type I, manifested by a variety of cognitive, motor, and behavioral abnormalities. Called also AIDS encephalopathy.
hypernatremic encephalopathy a severe hemorrhagic encephalopathy induced by the hyperosmolarity accompanying hypernatremia and dehydration.
hypertensive encephalopathy a complex of cerebral phenomena such as headache, convulsions, and coma that occur in the course of malignant hypertension.
hypoxic encephalopathy encephalopathy caused by hypoxia from either decreased rate of blood flow or decreased oxygen content of arterial blood; mild cases cause temporary intellectual, visual, and motor disturbances, and severe cases can cause permanent brain damage within five minutes. Called also anoxic encephalopathy.
lead encephalopathy brain disease caused by lead poisoning.
mitochondrial encephalopathy encephalopathy associated with mitochondrial abnormalities, such as melas syndrome and merrf syndrome.
portal-systemic encephalopathy (portasystemic encephalopathy) hepatic encephalopathy.
progressive subcortical encephalopathy Schilder's disease.
subacute spongiform encephalopathy (transmissible spongiform encephalopathy) prion disease.
traumatic encephalopathy
Wernicke's encephalopathy a neurological disorder characterized by confusion, apathy, drowsiness, ataxia of gait, nystagmus, and ophthalmoplegia; it is due to thiamine deficiency, usually from chronic alcohol abuse. It is almost invariably accompanied by or followed by korsakoff's syndrome and frequently accompanied by other nutritional polyneuropathies. See also wernicke-korsakoff syndrome.

transmissible spongiform encephalopathy

n. Abbr. TSE
Any of a group of neurodegenerative diseases of humans and other animals, including scrapie, bovine spongiform encephalopathy, and Creutzfeldt-Jakob disease, that are thought to be caused by prions and can be transmitted by contact from one individual to another.

transmissible spongiform encephalopathy

Encephalopathy marked by rapidly developing dementia or the sudden onset of psychiatric illnesses, often with myoclonus, ataxia, and aphasia. Death may occur within months of onset. These illnesses are believed to be caused by prions. Examples include kuru, mad cow disease (bovine spongiform encephalopathy), and Creutzfeldt-Jakob disease.
See also: encephalopathy
References in periodicals archive ?
But at a recent meeting, the FDA's Transmissible Spongiform Encephalopathies Advisory Committee voted 15-0 that this report should not change the agency's latest assessment of the risk of vCJD infection associated with plasma-derived factor VIII products licensed in the United States.
The long incubation period and always fatal outcome of CJD and other transmissible spongiform encephalopathies underscore the importance of efforts to minimize potential exposures of persons to prions.
* The guidance continues to advise hospitals and other healthcare facilities to consider the ACDP TSE (Advisory Committee on Dangerous Pathogens Transmissible Spongiform Encephalopathies) Working Group recommendations in cases of known or suspected TSEs (ACDP TSE, 2005).
Scientists report recent research into the most common of the transmissible spongiform encephalopathies, also known as prion diseases.
If the transducer is not protected by a pyrogen-free cover and it comes into contact with TSE's (Transmissible Spongiform Encephalopathies) it can not be sterilized by boiling or irradiating.
The patent for the Rapid Prion-Detection Assay protects this method of testing for all transmissible spongiform encephalopathies (TSEs) in animals and humans.
TSE's are Transmissible Spongiform Encephalopathies, a family of diseases including BSE in cows, scrapie in sheep and Creutzfeldt-Jackob Disease in humans.
At the request of the Food and Drug Administration (FDA) Transmissible Spongiform Encephalopathies (TSEs) Advisory Committee, Pall Corporation (NYSE: PLL) has presented the latest research results on its prion technology to remove TSE infectivity from blood.
Scrapie in sheep and goats, a fatal neurodegenerative disease, is a member of the family of transmissible spongiform encephalopathies (TSEs), which includes bovine spongiform encephalopathy (BSE) in cattle, chronic wasting disease in deer and elk, and Creutzfeldt-Jakob disease in humans.
Currently transmissible spongiform encephalopathies (TSEs), such as scrapie and bovine spongiform encephalopathy (BSE or mad cow disease), have slow incubation periods and are not easily detectable.
TABLE 1 Transmissible spongiform encephalopathies Species affected Prion disease Mink Transmissible mink encephalopathy Sheep and goats Scrapie Deer and elk Chronic wasting disease Cattle and bison Bovine spongiform encephalopathy Humans Creutzfeldt-Jakob disease; variant CJD, Gerstmann-Straussler-Scheinker disease, Kuru, fatal familial insomnia Species affected Transmissible to humans?

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