transgenic

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Related to Transgenes: transgenesis

trans·gen·ic

(trans-jen'ik),
Referring to an organism in which new DNA has been introduced into the germ cells by injection into the nucleus of the ovum.

transgenic

(trăns-jĕn′ĭk, trănz-)
adj.
1. Of, relating to, or being an organism whose genome has been altered by the transfer of a gene or genes from another species or breed: transgenic mice; transgenic plants.
2. Of or relating to the study of transgenic organisms: transgenic research.
n.
A transgenic organism.

transgenic

(of an organism) carrying GENETIC MATERIAL that it would not normally contain, as a result of TRANSGENESIS. In animals the archetypal example is the production of transgenic mice, so-called ‘supermice’. Transgenic animals that are DISEASE-resistant and that show increased GROWTH rates are being developed for food production. Transgenic crop plants that are resistant to HERBICIDES and disease are also under development. See also GENETIC ENGINEERING, ANTISENSE RNA.

transgenic

the product of transgenesis.

transgenic animal
one produced by transgenesis.
References in periodicals archive ?
Under the terms of the agreement Transgene will contribute both its OV design and engineering expertise, as well as its proprietary engineered Vaccinia virus, derived from its Invir.
Transgene previously reported a preclinical proof-of-concept data showing that an oncolytic Vaccinia virus encoding a sequence of anti-PD1 demonstrated better overall survival than the combination of separate single agents.
To construct the cumate-inducible transgene expression vector, the green fluorescent protein (GFP) or MyoD gene was inserted into the piggyBac cumate switch inducible vector (System Biosciences, Palo Alto, CA, USA) after NheI/NotI digestion and ligation.
These findings suggest that there was no deleterious or harmful effect of the GM sugarcane on the chick's health and no transgene fragment has transferred from GM crop to animal's blood neither in their vital tissues.
Electroporation utilizes a series of short electric pulses to permeate the cell membrane that make possible the formation of temporary pores on the surface of the target cells through which the transgene is introduced into the cytoplasm where it is then delivered to the nucleus by the cellular machinery [1].
In limb buds, the transgene is barely expressed at NF stage 51, and expression remains weak until NF stages 61-62.
The third approach involved introducing a transgene that would produce 'molecular decoys' to keep the virus' RNA polymerase molecules from transcribing other viral genes.
The transgenic mice produced by transfected spermatozoa or oocytes demonstrated that they were chimeras (because the expression of the transgenes occurs only in some organs) (Carballada et al.
One such technique has brought the limit of detection down to 10 copies of the transgene (the GM insert or a specific fragment of it).
Unstable expression of transgenes has been associated with gene silencing (Charrier et al.
Data suggest that complete containment of transgenes within alfalfa-seed--or hay-production fields would be highly unlikely using current production practices," the researchers commented in their 2000 paper.