transforming growth factor alpha

trans·form·ing growth fac·tor α (TGFα),

a cytokine made by tumor and transformed cells that is associated with growth and differentiation. It is also made in normal tissues during embryogenesis and in certain adult tissues.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
Expression of transforming growth factor alpha in human tissues: Immunohistochemical study and Northern blot analysis.
Abbreviations CCL: C-C motif chemokine ligand CXCL: C-X-C motif chemokine ligand CX3CL: C-X3-C motif chemokine ligand G-CSF: Granulocyte-colony stimulating factor GM-CSF: Granulocyte-macrophage colony-stimulating factor IFN: Interferon IL: Interleukin K: Keratin KC: Keratinocyte MMP-9: Matrix metalloproteinase-9 TGFa: Transforming growth factor alpha TNF[alpha]: Tumor necrosis factor alpha TNF[beta] Tumor necrosis factor beta VEGF: Vascular endothelial growth factor.
Sorvillo, "Expression of neu protein, epidermal growth factor receptor and transforming growth factor alpha in breast cancer.
2000), transforming growth factor alpha (Ojeda et al.
Growth factors also play a role, particularly estrogen and progesterone (which can independently affect the growth of breast cancer tumors), epithelial growth factor, transforming growth factor alpha, and others.
Transforming growth factor alpha (TGFA) is expressed at the medial edge epithelium of fusing palatal shelves during craniofacial development.
The transforming growth factor alpha (TGFA) gene is a well-studied candidate gene for oral clefting.
Lead researcher Magda Guerra-Crespo chronicles the success of a small protein called transforming growth factor alpha, which plays critical tissue-forming and developmental roles in humans from just after conception through birth and into old age.
Activation of the autocrine transforming growth factor alpha pathway in human squamous carcinoma cells.
Estrogen receptor alpha mediated induction of the transforming growth factor alpha gene by estradiol and 4-hydroxytamoxifen in MDA-MB-231 breast cancer cells.
Epidermal growth factor and transforming growth factor alpha concentrations in BPH and cancer of the prostate: their relationship with tissue androgen levels.

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