TFRC

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TFRC

A gene on chromosome 3q29 that encodes transferrin receptor, a protein required for development of erythrocytes and the nervous system.
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Serum hepcidin and soluble transferrin receptor in the assessment of iron metabolism in children on a vegetarian diet.
Transferrin receptor is necessary for development of erythrocytes and the nervous system.
Akkermans et al., "The value of soluble transferrin receptor and hepcidin in the assessment of iron status in children with cystic fibrosis," Journal of Cystic Fibrosis, vol.
Beguin, "Soluble transferrin receptor for the evaluation of erythropoiesis and iron status," Clinica Chimica Acta, vol.
(20.) Erhardt JG, Estes JE, Pfeiffer CM, Biesalski HK and NE Craft Combined measurement of ferritin, soluble transferrin receptor, retinol binding protein, and C-reactive protein by an inexpensive, sensitive, and simple sandwich enzyme-linked immunosorbent assay technique.
(4) More specialized tests to differentiate IDA from anemia of chronic disease (ACD) include hepcidin and transferrin receptor levels.
Soluble transferrin receptor was decreased to 1.3mg/L (N: 2.2-5).
This disease is caused by mutations in transferrin receptor 2 (TFR2) gene [2] that codes for two main isoforms, namely, Tfr2 alpha (Tfr2[alpha]) and Tfr2 beta (Tfr2[beta]), that show moderate homology to the type 1 transferrin receptor (Tfr1) [3].
Serum protoporphyrin levels, plasma hepcidin and transferrin receptor saturation assay14 are alternative tests.
Keywords: 17-[beta]-estradiol; Hepcidin; Intracellular labile iron; Ferroportin; Transferrin receptor; MCF-7; SKOV-3
Transferrin is can bind two [Fe.sup.3+] ions with very high affinity and donate iron to cells throughout the body via transferrin receptor 1 (TfR1) (Kovac et al., 2009).