jun(redirected from Transcription factor AP-1)
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Related to Transcription factor AP-1: Sp1 transcription factor
JUNA gene on chromosome 1p32-p31 that is the putative transforming gene of avian sarcoma virus 17, which interacts directly with specific target DNA sequences to regulate gene expression.
JUN maps to a chromosome region involved in both translocations and deletions in cancer.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
A family of oncogenes that can transform some normal cells (e.g., rat embryo cells) into cancer cells. All members of this family can bind to activating protein-1 (AP-1) sites and to specific DNA sequences. See: oncogene; transformation
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