basal factor

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basal factor

A generic term for any of the proteins that respond to activator signals, which position RNA polymerase at the starting point of a protein-coding region of a gene, resulting in transcription of genetic information from DNA, followed by translation into proteins.

Examples
TATA-binding protein and factors A, B, E, F, and H.
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References in periodicals archive ?
Transcription factor decoys are short, synthetic double-stranded DNA oligonucleotides that bind to transcription factors and prevent their interaction with the genome, effectively inhibiting a coordinated network of pathologic gene expression.
As shown in Figure 2, statistical analysis of network nodes in the transcription factor regulatory network diagram found more than 10 nodes that had 44 genes, of which there were 20 nodes that had more than 4 genes, including IL-6, ETS2, TNF, and OPN1MW (Table 4).
Rosengart, a team of researchers showed that administration of a cocktail made of transcription factors Gata4, Mef2c and Tbx5 (GMT) resulted in less scar tissue, or fibrosis, and up to a 50 percent increase in cardiac function in small animal models of the disease.
KLF/SP transcription factor family evolution: expansion, diversification, and innovation in eukaryotes.
Functional inactivation of the transcription factor Pax8 through oligomerization chain reaction.
The dataset provides abundant information on the sequences of transcription factor genes, which can be used for full-length cDNA cloning and functional studies.
Candidate A seemed too good as it is a basic region-containing transcription factor. I sought an excuse to explain why knockout of candidate A did not show the phenotype I expected.
To extract gene regulatory interactions from these networks, only interactions involved at least one human transcription factor were considered and a list of them were extracted from 33'34.
MYB transcription factor genes as regulators for plant responses: an overview.
Reduction in pancreatic transcription factor pdx-1 impairs glucose-stimulated insulin secretion.
In the present study, a novel MYB transcription factor gene CMYB1 was identified through transcriptome analysis in rice under cold stress.
As blastocyst development proceeds, the POU transcription factor, OCT4 (Pou5f1), becomes progressively restricted, first to the entire inner cell mass (ICM) and then to the epiblast (Palmieri et al., 1994; Nichols et al., 1998; Ralston and Rossant, 2005).

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