decoys are short, synthetic double-stranded DNA oligonucleotides that bind to transcription factors
and prevent their interaction with the genome, effectively inhibiting a coordinated network of pathologic gene expression.
As shown in Figure 2, statistical analysis of network nodes in the transcription factor
regulatory network diagram found more than 10 nodes that had 44 genes, of which there were 20 nodes that had more than 4 genes, including IL-6, ETS2, TNF, and OPN1MW (Table 4).
Rosengart, a team of researchers showed that administration of a cocktail made of transcription factors
Gata4, Mef2c and Tbx5 (GMT) resulted in less scar tissue, or fibrosis, and up to a 50 percent increase in cardiac function in small animal models of the disease.
KLF/SP transcription factor
family evolution: expansion, diversification, and innovation in eukaryotes.
Functional inactivation of the transcription factor
Pax8 through oligomerization chain reaction.
The dataset provides abundant information on the sequences of transcription factor
genes, which can be used for full-length cDNA cloning and functional studies.
Candidate A seemed too good as it is a basic region-containing transcription factor
. I sought an excuse to explain why knockout of candidate A did not show the phenotype I expected.
To extract gene regulatory interactions from these networks, only interactions involved at least one human transcription factor
were considered and a list of them were extracted from 33'34.
MYB transcription factor
genes as regulators for plant responses: an overview.
Reduction in pancreatic transcription factor
pdx-1 impairs glucose-stimulated insulin secretion.
In the present study, a novel MYB transcription factor
gene CMYB1 was identified through transcriptome analysis in rice under cold stress.
As blastocyst development proceeds, the POU transcription factor
, OCT4 (Pou5f1), becomes progressively restricted, first to the entire inner cell mass (ICM) and then to the epiblast (Palmieri et al., 1994; Nichols et al., 1998; Ralston and Rossant, 2005).