transaminase

(redirected from Transaminases)
Also found in: Dictionary, Thesaurus, Encyclopedia.
Related to Transaminases: alkaline phosphatase

transaminase

 [trans-am´ĭ-nās]
any of a group of enzymes that catalyze the reversible transfer of an amino group from a donor, usually an amino acid, to an acceptor, usually a 2-keto acid. Most use pyridoxal phosphate as a coenzyme.

transaminase

(trăns-ăm′ə-nās′, -nāz′, trănz-)
n.
Any of a group of enzymes that catalyze transamination. Also called aminotransferase.

a·mi·no·trans·fer·ase

(ă-mē'nō-trans'fĕr-ās)
[EC sub-group 2.6.1] Enzyme transferring amino groups between an amino acid to (usually) a 2-keto acid.
Synonym(s): aminopherase, transaminase.

transaminase

Any enzyme that catalyses the transfer of amino groups in the metabolism of amino acids (transamination). Also known as aminotransferase.

transaminase

an enzyme that transfers amino (NH2) groups. see TRANSAMINATION.
References in periodicals archive ?
Evaluations of plasma levels of acid phosphatase, alkaline phosphatase, alanine transaminase and aspartate transaminase
Therefore, it may be worthwhile to monitor patients for cardiac abnormalities despite signs of improving transaminases. In the case reported by Park et al.
Soon after treatment was started, however, his transaminases increased sharply.
New American College of Gastroenterology Guidelines for Transaminases
Tissue transglutaminase (TG) and IgA endomysiumspecific antibodies (EMAs) were evaluated for the CD because of the growth failure and elevated transaminase levels.
Serum transaminases increased again (ALT 466 IU/L and AST 656 IU/L; normal alkaline phosphatase) and a mild hypergammaglobulinaemia (1580 mg/dL) with normal IgA levels (135 mg/dL), positive anti-nuclear (ANA 1/80), anti-neutrophil cytoplasmic (ANCA 1/80), smooth-muscle (ASMA 1/40), and F-actin (23.3 U) antibody were detected, raising the suspicion of drug-induced autoimmune hepatitis.
On day 1 the values were as follows: serum bilirubin total: 2.9 mg%, direct fraction: 1 mg%, serum glutamic-oxaloacetic transaminase (SGOT): 3,093 units/L, serum glutamic-pyruvic transaminase (SGPT): 1,573 units/L, serum alkaline phosphatase (ALP): 85 units/L, serum total protein 6.8 g%, albumin: 3.6 g%, prothrombin time 7 s more than the control, and International Normalized Ratio = 1.55.
If alanine or aspartate transaminases are more than three times the upper limits of normal in asymptomatic patients without any other liver abnormalities, the enzymes should be rechecked within a week and statins should be stopped temporarily if the enzymes are still elevated.
Several studies report that the prevalence of the elevated transaminases in children varies according to the region, food, sanitation, the period of year and the quality of healthcare.
Serum transaminases are raised two to tenfold depending upon the severity of the disease.
INH hepatotoxicity is a common complication of anti- tuberculosis therapy, ranging in severity from asymptomatic elevation of serum transaminases to hepatic failure.
Despite their efficacy, common side effects including creatine phosphokinase (CPK) elevations, fatigue, weakness, myalgia, liver transaminases increase and rhabdomyolysis contribute to low adherence to treatment.