Toxic Oil Syndrome

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An epidemic that occurred around Avila, Spain, from 1981 to 1983, which was linked to ingestion of olive oil contaminated with rapeseed oil
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The lasting period of increased respiratory resistance and the distal interstitial lung commitment are similar to the toxic oil syndrome described by Kilbourne and colleagues but less toxic.
The Spanish toxic oil syndrome 20 years after its onset: a multidisciplinary review of scientific knowledge.
Two decades after contaminated cooking oil caused widespread sickness in Spain, patients with so-called toxic oil syndrome (TOS) continue to report neurologic symptoms.
CDC, in collaboration with the Toxic Oil Syndrome Research Centre (CISAT) of the Institute of Health Carlos Ill, Madrid, Spain, has established a MMWR mirror website in Spain.
Toxic oil syndrome, or TOS, appeared as a new disease in Spain in 1981 when thousands of people consumed denatured rapeseed oil sold illicitly as pure olive oil.
Key words: case-referent study, environmental food epidemic, exam, long-term effects, neurobehavioral tests, toxic oil syndrome.
The Spanish toxic oil syndrome 20 years after its occurrence: a multidisciplinary review of scientific knowledge.
1) reported on the possible relationship between several genetic polymorphisms that regulate enzymatic activities involved in the processing of multiple xenobiotics and the risk of Spanish toxic oil syndrome (TOS).
Acetylator phenotype in patients with toxic oil syndrome and in normal controls.
In 1981, the Spanish toxic oil syndrome (TOS) affected more than 20,000 people, and over 300 deaths were registered.