toxicity

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toxicity

 [tok-sis´ĭ-te]
the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
developmental toxicity the extent to which a toxin produces adverse effects on a developing embryo or fetus; see also teratogenesis.
maternal toxicity a toxic effect on a pregnant woman or nursing mother, as opposed to one affecting an embryo, fetus, or nursing infant.

tox·ic·i·ty

(tok-sis'i-tē),
The state of being poisonous.

toxicity

/tox·ic·i·ty/ (tok-sis´ĭ-te) the quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison.
O2 toxicity , oxygen toxicity serious, sometimes irreversible, damage to the pulmonary capillary endothelium associated with breathing high partial pressures of oxygen for prolonged periods.

toxicity

(tŏk-sĭs′ĭ-tē)
n. pl. toxici·ties
1. The quality or condition of being toxic.
2. The degree to which a substance is toxic.

toxicity

[toksis′itē]
Etymology: Gk, toxikon
1 the degree to which something is poisonous.
2 a condition that results from exposure to a toxin or to toxic amounts of a substance that does not cause adverse effects in smaller amounts.

toxicity

The sum of adverse effects 2º to exposure to a toxic substance, by mouth, through the skin or respiratory tract. See Amalgam toxicity, Botanical toxicity, Developmental toxicity, Digitalis/digoxin toxicity, Diphtheria toxicity, Excitotoxicity, Hashitoxicosis, Immunologic toxicity, Neurotoxicity, Nickel toxicity, Oxygen toxicity, Reproductive toxicity, Vitamin A toxicity.

tox·ic·i·ty

(tok-sis'i-tē)
The state of being poisonous.

toxicity

The quality or degree of poisonousness.

toxicity,

n the poisonous characteristics of a substance.

tox·ic·i·ty

(tok-sis'i-tē)
State of being poisonous.

toxicity (toksis´itē),

n the ability of a drug or poison to produce harm, especially to cause permanent injury or death. Usually distinguished from
allergenic properties.
toxicity, acute,
n a condition produced after short-term use of a toxic agent. See also dose, lethal, median; dose, lethal, minimum.
toxicity, chronic,
n a condition produced after long-term use of a toxic agent.
toxicity, fluoride,
n See fluoride toxicity.
Enlarge picture
Toxic shock syndrome.

toxicity

the characteristic or quality of being poisonous, especially the degree of virulence of a toxic microbe or of a poison. See also toxicosis.

toxicity rating
includes slightly toxic (with an oral LD50 in rats of 5000 to 15,000 mg/kg) up to supertoxic (with an LD50 of less than 5 mg/kg).
References in periodicals archive ?
These tools are expected to allow more rapid screening of chemicals for toxic effects and to provide mechanistic insight into a greater range and earlier stage of adverse outcomes associated with chemical exposures.
A modulation of the calcium level within the nucleus might have toxic effects leading to DNA damage and/or inhibition of DNA repair function.
However, the time of exposure to pollutants may be longer in vivo, and here in vitro we observed that long times of exposure allowed low concentrations to present toxic effects.
He notes, too, that some animal studies show that toxic effects of PBDEs and PCBs add to each other.
The linkers are designed to be stable in the bloodstream and to release the drug payload once inside target cells, thereby minimizing the toxic effects on normal tissues seen with traditional chemotherapy.
So we're using microarrays to figure out exactly what's going on, how the selenium is ameliorating the toxic effects.
He plans to examine whether the short-lived NO has toxic effects.
Nonetheless, Grimm and Kay bypassed the toxic effects by producing the therapeutic shRNA molecule at lower levels.
A task force from the Centers for Disease Control and Prevention is considering recommending that the cutoff be lowered to 5 pg/dL, although Goldman notes that many experts think there is no threshold for the toxic effects of lead.
Greenberg suggests that the clumps may protect nuclei from toxic effects of the unbound mutant proteins.
AMEX:LIV) a developer of innovative drugs, announced today, its Alzheimer's drug SP233, recently registered as Caprospinol, showed no toxic effects in standard preclinical assays used to evaluate its safety.
Finding effective ways to sort, interpret, and anticipate changes in expression is critical for moving these observations into a practical understanding of toxic effects.