The Agency intends to continue evaluating the application and, as needed, will announce future meeting dates in the Federal Register." The committee meeting had been planned to discuss new drug application 209500, lumateperone
tosylate capsules for oral administration, submitted by Intra-Cellular Therapies, for the treatment of schizophrenia.
The other reason to get serious about addressing primary axillary hyperhidrosis in pediatric patients is the recent approval of glycopyrronium
tosylate as a topical therapy, Dr.
M2 EQUITYBITES-January 10, 2019-Pii wins US FDA's approval for Bretylium
Tosylate Injection for ventricular fibrillation
Global Banking News-January 10, 2019-Pii wins US FDA's approval for Bretylium
Tosylate Injection for ventricular fibrillation
M2 PHARMA-January 10, 2019-Pii wins US FDA's approval for Bretylium
Tosylate Injection for ventricular fibrillation
Academic Pharmaceuticals, Inc., a partner with Hunt Valley-based Pharmaceutics International Inc., received FDA approval to develop Bretylium
Tosylate Injection USP, 500 mg/10 mL (50 mg/mL) Single-Dose Vials.
[34] Aparicio S, Alcalde R, Garcia B, Leal JM (2009) High-pressure study of the methylsulfate and
tosylate imidazolium ionic liquids.
Nexavar[R] Tablets 200 mg (Nonproprietary Name: Sorafenib
Tosylate Tablets) specific drug use investigation for unresectable hepatocellular carcinoma.
THE FOOD AND DRUG Administration has approved glycopyrronium
tosylate, an anticholinergic for the topical treatment of primary axillary hyperhidrosis in adults and children aged 9 years and older.
The fluorosubstitution of
tosylate was realized on a standard Neptis[R] synthesizer (ORA[TM]): after initial fluoride preparation (collection, drying, and Kryptofix activation), 1.0-2.0 mg of BOTs227 radiolabelling precursor was introduced and the reaction mixture was heated at 150[degrees]C for 10 min in DMSO.
The first finding was the realization of a new synthetic route to glycosyl fluorides by using a dehydrating reagent, 2-fluoro-1-methylpyridinium
tosylate (8) (Fig.
[Ts.sup.-] is
tosylate, C[H.sub.3] ([C.sub.6] [H.sub.4])S[O.sub.3.sup.-].