metoprolol

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Related to Toprol xl: metoprolol, Metoprolol succinate

metoprolol

 [mĕ-to´pro-lol]
a cardioselective beta-adrenergic blocking agent having a greater effect on β1-adrenergic receptors of the heart than on the β2-adrenergic receptors of the bronchi and blood vessels; the tartrate and succinate salts are used in the treatment of hypertension, angina pectoris, and myocardial infarction; administered orally or intravenously.

metoprolol

(mə-tō′prə-lôl′, -lōl′)
n.
A beta-blocker drug, C15H25NO3, used in its tartrate and succinate forms to treat hypertension and angina pectoris.

metoprolol

A beta-blocker used for hypertension and angina.
 
Adverse effects
Headache, fatigue, dizziness, dry cough, angiooedema.
 
Contraindications
Sinus bradycardia, cardiogenic shock, heart failure, heart block > 1st degree.

metoprolol

A cardioselective beta-blocker drug used to treat ANGINA PECTORIS, heart irregularities, high blood pressure (HYPERTENSION) and MIGRAINE. Brand names are Betaloc and Lopressor. The drug is also formulated with the diuretic HYDROCHLOROTHIAZIDE under the brand name Co-Betaloc.
References in periodicals archive ?
AstraZeneca Plc's Toprol XL, given before surgery to prevent heart complications, increases the danger of stroke or death, researchers said.
AstraZeneca's patent protection for Toprol XL expired last year, and the controlled-release drug has lost sales to generic copies.
So far this year, the company has launched a wide range of generics, including versions of AstraZeneca's Toprol XL, Pfizer Inc.'s Lipitor and Roche Holdings Ltd.'s Boniva and GlaxoSmithKline's Requip.
For example, last year we launched metoprolol succinate 50-mg tablets, a generic equivalent of Toprol XL [which is made by AstraZeneca PLC].
Actors presented a new prescription for one of the study drugs (Coumadin, Toprol XL, Depakote ER, Novolog MIX 70/30 insulin or Lantus insulin).
The actors attempted to purchase aspirin when they picked up Coumadin, and Sudafed PE with Toprol XL. Hidden cameras taped the results.
That total is likely to grow by the end of this year due to pending or recent patent expirations for such drugs as Ambien (for insomnia), and Norvasc and Toprol XL (both antihypertensives).
Patients using hypertension treatments, the PBM points out, could benefit from upcoming or recent patent expirations of Norvasc (amlodipine), Coreg (carvedilol) and Toprol XL (metoprolol extended release).
Of the two dozen most widely used brand name drugs in the "Rx Watchdog" report, the highest price increase (11.1%) was applied to Toprol XL 50-mg tablets, a cardioselective beta-blocker manufactured by AstraZeneca PLC.
The 10 drugs considered for the report include two generics--furosemide and hydrochlorothiazide--and eight brands: Celebrex, Fosomax, Lipitor, Norvasc, Plavix, Premarin, Toprol XL and Xalatan.
NEW YORK -- AstraZeneca PLC has received a challenge to its patents on Toprol XL from KV Pharmaceuticals Inc., a U.S.-based generic drug maker.