Also found in: Dictionary, Encyclopedia, Wikipedia.
Related to topoisomerase: DNA gyrase
an enzyme involved in mobilization and replication of DNA during cell division.
A type of enzyme converting (isomerizing) one topologic version of DNA into another; acts by catalyzing the breakage and reformation of DNA phosphodiester linkages.
[topo- + isomerase]
Either of two isomerase enzymes that alter the topology of DNA molecules by breaking and reconnecting coiled strands.