tosyl

(redirected from Toluenesulfonyl)

to·syl

(tō'sil),
Toluenesulfonyl radical, widely used to block amino groups in the course of organic syntheses of drugs and other biologically active compounds.
References in periodicals archive ?
5 mmol) in DMAc, carboxylic acid activating reagent p- toluenesulfonyl chloride (3.
p- Toluenesulfonyl chloride (Tos-Cl) is one of the most famous COOH activator which is widely used under homogenous esterification reaction conditions.
p- toluenesulfonyl chloride is an efficient and widely used reagent for such conversions and better than the conventional reagents like acid chlorides and acid anhydrides [17, 18] which may impart toxic side products and impurities in prodrugs.