Togaviridae

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To·ga·vir·i·dae

(tō'gă-vir'i-dē),
A family of viruses that includes two genera: Alphavirus, which includes eastern equine encephalitis, western equine encephalitis, and Venezuelan equine encephalitis virus, and Rubivirus, the rubella virus. Virions are 70 nm in diameter, enveloped, and ether sensitive; the capsid is of icosahedral symmetry, containing single-stranded positive sense RNA.

To·ga·vir·i·dae

(tō'gă-vir'i-dē)
A family of viruses that includes the following genera: Alphavirus, which includes eastern equine encephalitis; western equine encephalitis; Venezuelan equine encephalitis; and the rubella virus (Rubivirus).

To·ga·vir·i·dae

(tō'gă-vir'i-dē)
A family of viruses that includes the following genera: Alphavirus, which includes eastern equine encephalitis; western equine encephalitis; Venezuelan equine encephalitis; and the rubella virus (Rubivirus).

Togaviridae

a large family of viruses; presently two genera are defined: Alphavirus, which contains arthropod-borne viruses that cause eastern, western and Venezuelan encephalitis, and Rubivirus, which contains rubella virus of humans and is not arthropod-borne. Members of both genera have similar physicochemical properties. They are enveloped (toga = cloak) about 60 nm diameter, contain a single-stranded, plus sense RNA genome, replicate in the cytoplasm of cells and mature by budding through cytoplasmic membranes. Flaviviruses, which are also arthropod-borne, were once included in the family, but are now a separate family, Flaviviridae.
References in periodicals archive ?
BCX4430, an RNA dependent-RNA polymerase inhibitor, has demonstrated broad-spectrum activity against 20 RNA viruses in filoviruses, togaviruses, bunyaviruses, arenaviruses, paramyxoviruses, coronaviruses and flaviviruses.
The X domain corresponds to a macro domain found in the nonstructural polyproteins of several positive-stranded viruses such as togaviruses and coronaviruses (35-37).
Such viruses include Ebola and Marburg viruses, Nipah and Hendra viruses, severe acute respiratory syndrome-like coronavirus, rabies and other lyssaviruses, togaviruses, flaviviruses, bunyaviruses, and members of the family Reoviridae (11-13).