tocolytic

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tocolytic

 [to″ko-lit´ik]
1. pertaining to or causing tocolysis (postponement of preterm labor).
2. an agent that does this, such as ritodrine hydrochloride or another β2-adrenergic receptor agonist.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

to·co·lyt·ic

(tō'kō-lit'ik),
Denoting any pharmacologic agent used to arrest uterine contractions; often used in an attempt to arrest premature labor contractions, for example, ritodrine or terbutaline.
[G. tokos, childbirth, labor, + lysis, loosening]
Farlex Partner Medical Dictionary © Farlex 2012

tocolytic

Obstetrics adjective Referring to an agent with tocolytic activity noun Any of a number of beta agonists-eg isoxsuprine, terbulatine, ritodrine, used to halt the progression of preterm labor. See Ritodrine.
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

to·co·lyt·ic

(tō'kō-lit'ik)
Denoting any pharmacologic agent used to arrest uterine contractions; often used in an attempt to arrest premature labor contractions.
[G. tokos, childbirth, labor, + lysis, loosening]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Tocolytic

A medication that inhibits uterine contractions.
Mentioned in: Prenatal Surgery
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
References in periodicals archive ?
There is limited evidence that use of nifedipine, rather than a beta-agonist (Isoxsuprine), is associated with improved short-term neonatal outcome, because Nifedipine is a well-tolerated, very effective and very safe tocolytic agent when seen with respect to Isoxsuprine with less maternal complications in management of preterm labour.
In addition, Khan et al., in a systematic review and meta-regression analysis, evaluated the safety of nifedipine as a tocolytic agent in preterm labor and as an antihypertensive agent in the treatment of hypertension in pregnancy.
Objective: To find out the effectiveness of oral nifedipine as a tocolytic agent in external cephalic version.
IP belongs to the betamimetics group among tocolytic agents and reports state that maternal and foetal side effects may be observed during IP administration for tocolysis.14
The aim of using tocolytic agents in preterm labor is to delay the delivery at least 48 hr, given the proven effectiveness of corticosteroids for improving neonatal outcomes.
Betamimetics are widely used as tocolytic agents. Although they have been shown to prolong pregnancy by 24 to 48 hours, they have not decreased adverse perinatal or neonatal outcomes (LOE: 1).
MAO inhibitors may produce a hypertensive crisis when used in the presence of tocolytic agents and have been associated with congenital anomalies in animal studies.
(The term, "tocolytic" is applied to an agent that effectively stops uterine contractions.) Researchers at Duke University and the University of North Carolina abstracted data from 75 studies of tocolytic agents and conducted a meta-analysis using 24 studies.
Prior to toxin exposure (Example cocaine) and prolonged use of tocolytic agents, i.e.
Its secure use on record shall make it an alternative to other tocolytic agents, like salbutamol, ritodrine or calcium channel blockers for pre-term labour and could make a major involvement in the management of pre-term labour.
(4) Once preterm labor has begun, little in the way of successful intervention is possible, beyond short-term prolongation of pregnancy with tocolytic agents to allow for corticosteroid administration.