tiopronin


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tiopronin

 [ti-o´pro-nin]
a thiol compound used in treatment of cystinuria and prevention of kidney stones; administered orally.
References in periodicals archive ?
Commercial launch for THIOLA EC (tiopronin) is underway following approval by U.S.
Tiopronin is a medication used to aid in preventing the formation of cystine kidney stones.
Those studies demonstrated the protective effects of N-acetylcysteine [17], D-methionine [18], L-methionine [19], ebselen and allopurinol [20], tiopronin [21], vitamin E, [22] and steroids [23, 24] against cisplatin ototoxicity.
The numerous otoprotective agents utilized in clinical and animal studies include Amifostine, D-or L-Methionine, methylthiobenzoic acid, lipoic acid, tiopronin, glutathione ester, sodium thiosulfate [83], Melatonin [84], Vitamin E [85], N-acetylcysteine [86], Dexamethasone [87], and Resveratrol [88].
Imprimis will supply all formulations included under its Imprimis Cares formulary including the patent-pending tiopronin delayed-release formulations, a lower cost alternative to Thiola; pyrimethamine and leucovorin formulations, an alternative to Daraprim; the company's proprietary Dropless Therapy injectable and LessDrops topical formulations; as well as additional compounded drug formulations for patient populations that may not have available alternatives to increasingly expensive branded medications and lacking meaningful generic competition.
Most of the latter patients received conventional liver-protecting treatment, for instance, polyene phosphatidylcholine, tiopronin.
Pharmaceutical company Retrophin (NasdaqGM:RTRX) revealed on Thursday the launch of an agreement for licensing the US marketing rights of its Thiola (tiopronin) for an undisclosed value.
One batch with hydrogen tetrachloroaurate(III) trihydrate (1 equiv) and N-(2-mercaptopropionyl)glycine (tiopronin) (5.5 equiv) was codissolved in 35mL of 6:1 methanol/acetic acid, resulting in a ruby red solution.
Alternatively, gold nanoparticles can be directly synthesized in the presence of thiolated ligands, including chemically functional species such as tiopronin, glutathione, and coenzyme A [29-31], to circumvent the need for ligand exchange.
* Tiopronin (Thiola), which reduces the amount of cystine in the urine.