SLCO1C1

(redirected from Thyroxine transporter)

SLCO1C1

A gene on chromosome 12p12.2 that encodes a protein which mediates Na+-independent high-affinity transport of organic anions (e.g., thyroxine and rT3) and lower-affinity transport of other substrates (e.g., triiodothyronine, 17-beta-glucuronosyl oestradiol, oestrone-3-sulfate and sulfobromophthalein). SLCO1C1 is thought to play a major role in regulating T4 flux in the brain.
References in periodicals archive ?
Meier, "Identification of a novel human organic anion transporting polypeptide as a high affinity thyroxine transporter," Molecular Endocrinology, vol.
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