thyrotrope

(redirected from Thyrotrophs)

thyrotroph

 [thi´ro-trōf]
a type of basophil in the adenohypophysis that secretes thyrotropin.

thyrotrope

/thy·ro·trope/ (thi´ro-trōp) thyrotroph.

thyrotrope

one of the basophils (beta cells) of the adenohypophysis, the granules of which secrete thyrotropin.
References in periodicals archive ?
Ultrastructurally, well-differentiated adenomatous thyrotrophs resemble normal ones, whereas poorly differentiated adenomas were composed of elongated angular cells with irregular nuclei, poorly developed rough endoplasmic reticulum, long cytoplasmic processes, and sparse small secretory granules (50–200 nm) that mostly line up along the cell membrane [Figure 2].
Pit-1 gene expression is essential for the growth of some regulatory processes in the body of animals such as the ability of normal survival, differentiation and development of the three cell types of adenohypophysis, namely somatotrophs, lactotrophs and thyrotrophs [2,3].
It is a glycoprotein secreted by the thyrotrophs in the anteromedial portion of the adenohypophysis.
12,13) The periodic acid-Schiff stain is very helpful to identify corticotrophs and is valuable to identify hyperplastic thyrotrophs that exhibit cytoplasmic periodic acid-Schiff-positive droplets.
Both TRH and somatostatin are also detectable by radioimmunoassay in thyrotrophs at embryonic day 14 (Harvey et al.
The anterior lobe consists of several different cell types (somatotrophs, mammotrophs, corticotrophs, thyrotrophs, and gonadotrophs), which are involved in the biosynthesis and secretion of key hormones (growth hormone, prolactin, adenocorticotropic hormone, thyroid-stimulating hormone, and follicle-stimulating hormone/ luteinizing hormone, respectively) that regulate multiple, diverse, and important physiologic and metabolic functions in the human body (2).
3] levels, and a low TSH level until the pituitary thyrotrophs recover from chronic suppression.
Endocrinologists have the impression that we are in the midst of an epidemic of "unhappy" thyrotrophs.
Investigations revealed hyperprolactinemia and ACTH deficiency with normal function of the rest of the pituitary hormone-producing cells including thyrotrophs.
In hypothalamic disease, there is a delayed and exaggerated response to TRH because the thyrotrophs take some time to "wake up" after a prolonged lack of stimulation by endogenous TRH.