thyroid epithelial cell

(redirected from Thyrocyte)

thyroid epithelial cell

The primary epithelial cell of the thyroid gland.
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.
References in periodicals archive ?
Anti-thyroid peroxidase (TPO), located at the apical membrane of the thyrocyte, is essential for thyroid hormone synthesis, catalysis of iodine oxidation, iodination of tyrosine residues in Tg (Thyroglobulin) and coupling of the iodothyrosines into thyroxine (T4) and triiodothyronine (T3).
Most patients present with mild signs of thyrotoxicosis and possible neurological features, due to pituitary mass; they often have thyroid nodule disease.[sup][2],[24] Apparently, TSH is the primary mediator of thyrocyte proliferation.[sup][25] TSHomas may be associated with thyroid diseases, and in diagnosing TSHoma, the possibility of thyroid disease should be investigated and followed up.
Additionally, in vitro studies have shown that lithium increases thyrocyte proliferation by Wnt/[beta] signaling (5,6).
Sodium ioidide symporter glycoprotein is necessary for the efficiency of RAI treatment as it is responsible for the iodine transport across the thyrocyte basal membrane.
The thyrotropin receptor and the regulation of thyrocyte function and growth.
This defect is the result of impaired expression/function of the sodium/iodine symporter (NIS) or thyroperoxidase (TPO) caused by oncogene-activated signaling that leads to thyrocyte dedifferentiation [3-5].
The effects of diosgenin in a mouse model of Graves' disease were also investigated and it was observed that this steroid can relieve goiter through the inhibition of thyrocyte proliferation.
Additionally, iodine deficiency of the area results in an increase of serum TSH which represents the major regulator of the growth and the thyrocyte's differentiation and proliferation [30, 31].
(1987) Enhancement of thyrocyte HLA class II expression by thyroid stimulating hormone.