Researchers at the University of Minnesota have found triptolide, an extract of the Chinese herb thunder god vine
(Tirpterygium wilforii), which suppresses GRP78, a protein that protects cells from dying, is more abundant in cancer cells and tissue than in normal organs and is thought to play a role in helping pancreatic cancer cells survive and thrive.
A spokeswoman for Arthritis Research UK commented: "Previous trials of TwHF, also known as thunder god vine
, have shown it has some anti-inflammatory properties and immunosuppressive actions, making the compound a potentially useful substance for treating rheumatoid arthritis.
Celastrol, a potent anti-inflammatory agent extracted from the so-called "thunder god vine
" has been seen to suppress a protein known as p23.
Lei gong teng or thunder god vine
are the traditional Chinese names for extracts of the flowers, leaves and roots of Tripterygium wilfordii Hook F (TwHF).
Thunder god vine
, an ancient Chinese herbal remedy, helps reduce inflammation in people with rheumatoid arthritis (RA), according to a study published August 18, 2009 in the Annals of Internal Medicine.
A serious warning was issued about thunder god vine
for rheumatoid arthritis.
London, Mar 4 (ANI): A natural product isolated from a traditional Chinese medicinal plant commonly known as thunder god vine
and used for rheumatoid arthritis could be a starting point for developing new anticancer drugs, suggest scientists.