thujone


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Related to thujone: wormwood, absinthe

thu·jone

(thū'jōn),
Chief constituent of cedar leaf oil; a stimulant and convulsant similar to camphor.

thujone

(tho͞o′jōn′, thyo͞o′-)
n.
A ketone, C10H16O, that is thought to be a neurotoxin and is found in certain plants such as the wormwood Artemisia absinthium, an ingredient in absinthe.

thujone

Pharmacognosy
A ketone and a monoterpene found in nature in alpha and beta forms, which is present in the leaves of cedars (Thuja occidentalis) and many other plants (e.g., junipers, mugwort, oregano, common sage, tansy, wormwood). It acts on GABA and 5HT3 receptors and has been used topically. In contrast to popular belief, the spirit absinthe contains only minute amounts of thujone, which has long been held responsible for absinthe’s alleged psychedelic effects.

Toxicity
Internal ingestion is associated with convulsions.
References in periodicals archive ?
(33) Another component of the used extract is thujone, with well-known neuroprotective effects.
Thujone (trans), [gamma]-terpinene, nerol and myrtenol inhibited all tested bacteria in wide range of MICs (1-50 [micro]L/mL).
Absinthium have been reported.3 One of these a- thujone has an effect on central nervous system (CNS).
The discussion, which will come to a head at a meeting of the parliament in the French city of Strasbourg next week, focuses on the amount of the naturally occuring chemical thujone that must be present in the drink, if at all.
Thujone and geraniol present lower effect (Perry & al., 2001) as well as eugenol and thymol, and other methylisopropylphenols (GUILLEN & MANZANOS, 1999).
Carvone was observed to be more toxic than bicyclic compounds such as verbinol and thujone [10].
Ada cayi yapraklarinin damitilmasi ile elde edilen ada cayi yagi; salvene, pinene, camphor, cineole, borneol, thujone, sponin, diterpene, phenolic asit, salviatanin, ursokolik asit, kafeik asit ve flavonoidleri icerir (1-3).
(18) Screening for metals was conducted using semi-quantitative inductively coupled plasma mass spectrometry (ICP-MS) (17, 19) The absinthe from Switzerland was quantitatively analyzed for thujone. (20) Wine and beer samples were screened for aflatoxins using a commercially available test-kit (Aflacard Total, R-Biopharm, Darmstadt, Germany).
from 1912 until 2007, when the Food and Drug Administration began permitting formulations with minimal amounts of thujone, a psychoactive chemical in wormwood.
The high alcohol content of the drink as well as the presence of the hallucinogenic thujone has seen this drink widely banned.
sclarea (S5) was the only one to present distinct compounds in relation to the other species, having as major compounds linalool (29.36%), linalyl acetate (18.35%) and [alpha]-terpineol (11.18%) of a total of 81.48%, thus showing low contents of thujone, camphor and 1,8-cineole (Table 5), corroborating the work of Foray et al.
Don)) is mainly caused by the presence of antimicrobial compounds, notably thujone and thujaplicin, in the heartwood.