are administered intravenously and are necessary to give as soon as possible after the patient progresses the signs and symptoms of STEMI; the earlier they are given the better will be noticed.
can cause serious bleeding and before they are given paramedics must be reasonably sure of the diagnosis.
Streptokinase is secreted by streptococci.1 It was the first thrombolytic drug
that was used for myocardial infarction.
However, with the removal of this thrombolytic drug
from the market in 1999 and no other to immediately replace it, this was no longer an option.
Other significant determinants of an increased complication rate were smoking and a Killip class of II-IV The analysis also showed that two factors were linked with significant protection against complications: treatment with a thrombolytic drug
, and treatment with an anxiolytic drug, which was associated with a 44% drop in the rate of complications.
The study enrolled 204 patients who had an ST-segment elevation MI and were successfully reperfused with either a percutaneous coronary intervention or a thrombolytic drug
. The study was done at 16 medical centers in Germany and one in Switzerland.
Where thrombolysis is contraindicated or there is a need to reduce thrombolytic drug
exposure or accelerate treatment times, PMT or surgical venous thrombectomy should be considered.
If you are having an ischemic stroke (the type produced by a blood clot), the severity can be reduced if you receive a "clot-busting" thrombolytic drug
within three hours of stroke onset.
Streptokinase is currently the most cost-effective thrombolytic drug
available (Ghosh, Pulicherla, Rekha, Rao, & Rao, 2012); however, it lacks the other characteristics to make it the ideal thrombolytic medication.
The standard thrombolyticdrug cocktail should no longer simply be the thrombolytic drug
(usually a plasminogen activator) and unfractionated heparin.
(2006) Development of an in vitro model to study clot lysis activity of thrombolytic drugs
. Thromb J 4: 14.
act rapidly to dissolve unwanted blood clots (thrombi) in blood vessels.