tiopronin

(redirected from Thiola)

tiopronin

 [ti-o´pro-nin]
a thiol compound used in treatment of cystinuria and prevention of kidney stones; administered orally.
References in periodicals archive ?
Retrophin's R&D efforts are supported by revenues from the Company's commercial products Chenodal, Cholbam and Thiola.
Retrophin announced that the FDA has approved 100 mg and 300 mg tablets of Thiola EC, a new enteric-coated formulation of Thiola, to be used for the treatment of cystinuria, a rare inherited disorder that causes a buildup of cystine levels in the urine resulting in the formation of recurring cystine kidney stones.
It too had form for hiking drug prices, including raising the price of kidney medication Thiola by 2,000%.
Imprimis will supply all formulations included under its Imprimis Cares formulary including the patent-pending tiopronin delayed-release formulations, a lower cost alternative to Thiola; pyrimethamine and leucovorin formulations, an alternative to Daraprim; the company's proprietary Dropless Therapy injectable and LessDrops topical formulations; as well as additional compounded drug formulations for patient populations that may not have available alternatives to increasingly expensive branded medications and lacking meaningful generic competition.
Desulfurizati on of aromatic sulfur compounds much complicated as comp are with desulfurization of aliphatic sulfur compounds [8].hig h viscosities and high API gravities crude oil contains high a mount of sulfur content and also a complex sulfur compounds, acyclic aliphatic sulfides such as thioethers and cyclic thiola ne can be removed easily by a process of thermal treatment or commonly known as HDS [9].
The company said the increase in net product sales is due to the acquisition and subsequent commercial launch of two additional orphan disease products, Thiola and Cholbam.
* Tiopronin (Thiola), which reduces the amount of cystine in the urine.
According to Keith, Thiola (tiopronin, also referred to as 2-mercaptopropionylglycine or 2-MPG), has fewer side effects, but one of them is the depletion of the owner's bank account.
* Tiopronin (Thiola) may be used to reduce the amount of cystine in the urine.
Streem called tiopronin (Thiola) the drug of choice because it is less likely than D-penicillamine to cause side effects.
If cystine stones cannot be controlled by drinking more fluids, the doctor may prescribe the drug Thiola.[R] This medication helps reduce the amount of cystine in the urine.