4], the thiol groups
in chitosan and the double bonds in PEGDA easily met and reacted, resulting in the rapid gelation before the dispersive phases changed into smaller phases (Fig.
Modena, Chemistry of thiol group
, in Oxidation of Thiols.
This fact could be attributed to the thiol groups
, which may chelate better the [Fe.
The thiol group
is a far stronger nucleophile than the amino groups.
Thus, it is apparent that the reactivity of the thiol group
for unsaturated double bonds is larger than that of hydroxyl and carboxyl groups.
The thiol group
of Hcy allows it to form a disulfide bond with other thiol-containing molecules, such as Hcy itself, cysteine, and the cysteine residue of plasma proteins.
These methods often use benzofurazanes as derivatization reagents that are considered to be specific for the thiol group
of HCY (5-14).
Correct orientation of a surface capture antibody also increases the potential use of antibody fragments, which can be tailored for solid-phase coupling by the introduction of a site-specific group, such as a thiol group
, through genetic engineering (Meretoja et al.
3) by inserting a specific reactive amino acid, such as a cysteine with its reactive -SH thiol group
, at a selected site (Fig.
The glutathione adduct formation is associated with the [beta] chain but not the a chain because Cys-[beta]93 provides the only accessible thiol group
at the surface of the Hb molecule.
DTT protects thiol function from oxidation during the deproteinization step but did not contribute to an improvement of recoveries for Me6-MP, the thiol group
being protected from oxidation by a methyl function.
Pb is reported to bind the thiol groups
situated in the hepatocyte membranes inducing leakage of cytosolic enzymes principally ASAT and ALAT .